摘要
目的:观察贻贝粘蛋白(Mussel adhesive protein,MAP)联合超完美脉冲光(Advanced optimal pulse technology,AOPT)治疗敏感性皮肤的疗效及安全性。方法:敏感性皮肤患者共60例,随机分为对照组和观察组,每组30例。对照组采用AOPT治疗,观察组采用AOPT联合MAP治疗。4周治疗1次,共治疗3次。治疗结束后28 d比较两组患者治疗后的临床疗效。结果:治疗后,两组临床症状评分均降低,且观察组低于对照组(P<0.05);治疗后,观察组治疗总有效率为93.33%(28/30),高于对照组的73.33%(22/30)(P<0.05);治疗后,两组皮肤pH值均降低、角质层含水量和皮脂含量均升高,且观察组皮肤pH值低于对照组,角质层含水量高于对照组(P<0.05);治疗后,两组DLQI评分均降低,且观察组低于对照组(P<0.05)。结论:AOPT联合MAP有利于改善敏感性皮肤患者临床症状,提高患者治疗效果,同时对改善患者皮肤屏障功能、提升患者生活质量有积极意义。
Objective To observe the efficacy and safety of mussel adhesive protein(MAP)combined with advanced optimal pulse technology(AOPT)in the treatment of sensitive skin.Methods 60 patients with sensitive skin were randomly divided into control group(30 cases)and observation group(30 cases).The control group was treated with AOPT,while the observation group received AOPT combined with MAP.Both groups were treated for 3 times(once every 4 weeks).The clinical efficacy of the two groups was compared at 28 days after the end of treatment.Results After treatment,the clinical symptoms scores were decreased in both groups,and the observation group had lower scores(P<0.05).The total effective rate in observation group after treatment was 93.33%(28/30),which was higher than 73.33%(22/30)in control group(P<0.05).After treatment,the skin pH value in the two groups was declined while the water content of stratum corneum and sebum content were enhanced,and the skin pH value in observation group was lower while the water content of stratum corneum was higher compared to control group(P<0.05).The DLQI score in the two groups was reduced after treatment,and the score in observation group was lower compared with that in control group(P<0.05).Conclusion AOPT combined with MAP is beneficial to improving the clinical symptoms and enhancing the therapeutic effect of patients with sensitive skin,and it has positive significance for improving the skin barrier function and enhancing the quality of life of patients.
作者
李牧桑
祁薇
张跃伟
LI Musang;QI Wei;ZHANG Yuewei(Department of Cosmetic Dermatology,Hangzhou JustHer Medical Cosmetology Hospital,Hangzhou 310000,Zhejiang,China;Department of Cosmetic Dermatology,Hangzhou Liantianmei Medical Cosmetology Hospital,Hangzhou 310000,Zhejiang,China;Department of Cosmetic Dermatology,Ningbo One and Only Cosmetic Hospital,Ningbo 315000,Zhejiang,China)
出处
《中国美容医学》
CAS
2024年第4期99-102,共4页
Chinese Journal of Aesthetic Medicine
关键词
贻贝粘蛋白
超完美脉冲光
敏感性皮肤
皮肤屏障
生活质量
mussel adhesive protein
advanced optimal pulse technology
sensitive skin
skin barrier
quality of life
