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围手术期肺结节患者抑郁焦虑的影响因素:一项前瞻性研究

The influencing factors of depression and anxiety disorder in perioperative patients with pulmonary nodules:a prospective study
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摘要 目的 研究围手术期肺结节患者抑郁焦虑状态的影响因素及评估手术对其的影响。方法 收集2023年1月至2023年9月北京医院胸外科就诊的肺结节患者共140例,于术前收集患者的一般情况、人格特点等信息,并通过抑郁自评量表(Self-rating Depression Scale SDS)、焦虑自评量表(Self-rating Anxiety Scale,SAS)、匹兹堡睡眠质量指数(Pittsburgh Sleep Quality Index,PSQI)、简明生活质量与满意程度问卷评定患者术前焦虑、抑郁、睡眠、生活质量等情况,并同时为之分级;术后1个月、3个月、6个月、12个月随访,通过上述量表评定患者术后焦虑、抑郁、睡眠质量、生活质量状态并分级,并与术前比较。结果 术前患者抑郁54例(38.6%),焦虑24例(17.1%),抑郁伴焦虑18例(12.9%)。经过多因素Logistic回归分析发现精神质(P=0.048)、神经质(P=0.009)是术前抑郁状态的危险因素,同时也是术前焦虑状态的危险因素(P=0.006,P=0.007)。术前与术后患者对比,患者的抑郁状态或焦虑状态的差异无统计学意义。而病理的良恶性对患者术后抑郁或焦虑与否无关。结论 典型的神经质和精神质的患者与抑郁、焦虑状态存在关联。 Objective To investigate the influencing factors of depression and anxiety in patients diagnosed with pulmonary nodules and evaluate the impact of surgery on them.Methods A total of 140 patients diagnosed with pulmonary nodules in the Department of Thoracic Surgery of Beijing Hospital from January 2023 to September 2023 were collected.The general information and personality characteristics of the patients were collected before surgery.The Self-rating Depression Scale(SDS),Self-rating Anxiety Scale(SAS),Pittsburgh Sleep Quality Index(PSQI),concise quality of life and satisfaction questionnaire were used to evaluate the preoperative anxiety,depression,sleep and quality of the patients’lives.The patients were followed up at 1 month,3 months,6 months and 12 months after operation.The postoperative anxiety,depression,sleep quality and quality of life of the patients were evaluated and graded by the above scales,and compared with those before operation.Results A total of 140 patients were included in this study.There were 54 patients(38.6%)with depression,24 patients(17.1%)with anxiety,and 18 patients(12.9%)with depression and anxiety.After multivariate logistic regression analysis,we found that psychoticism(P=0.048)and neuroticism(P=0.009)were risk factors for preoperative depression.They were also risk factors for preoperative anxiety(P=0.006,P=0.007).And there was no significant difference in depression or anxiety between preoperative and postoperative patients.Moreover,the pathological characteristics of the patients were not related to postoperative depression or anxiety in patients.Conclusions Patients with typical neuroticism and psychoticism are associated with depression and anxiety.
作者 吴凡隽 吴江宇 佟宏峰 于瀚博 李东航 田文鑫 孙耀光 焦鹏 Wu Fanjuan;Wu Jiangyu;Tong Hongfeng;Yu Hanbo;Li Donghang;Tian Wenxin;Sun Yaoguang;Jiao Peng(Department of Thoracic Surgery,Beijing Hospital,National Center for Gerontology,Institute of Geriatric Medicine,Beijing 100730,China;Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China)
出处 《中国医学前沿杂志(电子版)》 CSCD 北大核心 2024年第4期34-40,共7页 Chinese Journal of the Frontiers of Medical Science(Electronic Version)
关键词 肺结节 抑郁 焦虑 Pulmonary nodule Depression Anxiety
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