摘要
目的:探讨阿奇霉素联合头孢克肟在小儿肺炎中的效果。方法:选择2022年1—12月潜江市中心医院儿科收治的92例小儿肺炎患儿作为研究对象,根据随机数表法将患儿分为对照组和研究组,各46例。对照组使用头孢克肟治疗,研究组使用阿奇霉素联合头孢克肟治疗。比较两组住院时间、肺啰音消失时间、体温恢复时间、咳嗽消失时间,炎症因子水平变化,治疗效果。结果:与对照组比较,研究组住院时间、肺啰音消失时间、体温恢复时间、咳嗽消失时间更短,差异有统计学意义(P<0.05)。治疗后,两组白细胞计数、血小板聚集率、C反应蛋白、降钙素水平低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05)。研究组总有效率高于对照组,差异有统计学意义(P<0.05)。结论:小儿肺炎使用阿奇霉素联合头孢克肟治疗,住院时间有效缩短,疾病症状缓解更快,炎症因子水平有效降低,治疗效果更显著。
Objective:To investigate the effect of Azithromycin combined with Cefixime in children with pneumonia.Method:Ninety-two children with pneumonia who treated in the Department of Pediatrics of Qianjiang Central Hospital from January to December 2022 were selected as the study objects,they were divided into the control group and the study group according to the random number table method,46 case in each group.The control group was treated with Cefixime,and the study group was treated with Azithromycin combined with Cefixime.The hospitalization time,lung rale disappearance time,body temperature recovery time,cough disappearance time,inflammatory factor level changes and treatment effect were compared between two groups.Result:Compared with the control group,the hospitalization time,lung rale disappearance time,body temperature recovery time and cough disappearance time of the study group were shorter,and the differences were statistically significant(P<0.05).After treatment,the levels of white blood cell count,platelet aggregation rate,C-reactive protein and calcitonin in two groups were lower than those before treatment,and those in the study group were lower than the control group,the differences were statistically significant(P<0.05).The total effective rate of the study group was higher than that of the control group,the difference was statistically significant(P<0.05).Conclusion:Azithromycin combined with Cefixime in the treatment of children with pneumonia can effectively shorten the hospitalization time,relieve the symptoms of disease faster,effectively reduce the level of inflammatory factors,and the treatment effect is significant.
作者
赵胜超
石盾
黄玉玲
魏新冬
ZHAO Shengchao;SHI Dun;HUANG Yuling;WEI Xindong(Qianjiang Central Hospital,Qianjiang 433100,China;不详)
出处
《中外医学研究》
2024年第13期38-41,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
基金
湖北省自然科学基金项目(WJ2021MB923)。
关键词
头孢克肟
阿奇霉素
炎症因子
肺啰音
肺炎支原体
咳嗽
Cefixime
Azithromycin
Inflammatory factors
Pulmonary rales
Mycoplasma pneumoniae
Cough