摘要
中医学认为,心脾在生理、病理上紧密联系,脾病可致心病,心病可从脾治。内质网稳态和应激状态与中医脾的生理、病理相似,可能是中医脾功能在亚细胞层面的体现。内质网应激是慢性冠脉综合征的致病因素,通过参与动脉粥样硬化形成与血管内皮功能障碍促进慢性冠脉综合征进展,这与中医脾参与痰瘀形成,导致胸痹的过程相似。内质网应激与慢性冠脉综合征的联系为中医从脾治心、心脾同治提供参考,为中医药防治慢性冠脉综合征提供思路。
According to TCM,the heart and spleen are closely linked in physiology and pathology;spleen diseases can lead to heart diseases,and heart diseases can be cured from the spleen.Endoplasmic reticulum homeostasis and stress are similar to the physiology and pathology of the spleen,and may be a reflection of spleen function at the subcellular level.Endoplasmic reticulum stress is a pathogenic factor in chronic coronary syndromes,and promotes the progression of chronic coronary syndromes by participating in the formation of atherosclerosis and vascular endothelial dysfunction,which is similar to the process of spleen involvement in the formation of phlegm and blood stasis leading to chest obstruction.The connection between ERS and chronic coronary syndromes provides a reference for the treatment of the heart from the spleen and treating the heart and spleen together in TCM,and provides ideas for the prevention and treatment of chronic coronary syndromes in TCM.
作者
徐镕锌
王晗
XU Rongxin;WANG Han(Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China)
出处
《中国中医药图书情报杂志》
2024年第4期19-23,共5页
Chinese Journal of Library and Information Science for Traditional Chinese Medicine
基金
江苏省卫生健康委科研课题(BJ20021)
江苏省老年健康科研项目(LKZ2023002)。
关键词
内质网应激
慢性冠脉综合征
从脾治心
endoplasmic reticulum stress
chronic coronary syndrome
treating the heart from the spleen
