摘要
目的系统评价经皮微球囊压迫术(percutaneous balloon compression,PBC)和经皮射频热凝术(percutaneous radiofrequency thermocoagulation,PRT)治疗三叉神经痛(trigeminal neuralgia,TN)的疗效。方法计算机检索中国知网、万方数据、互联网、PubMed、EMbase、Cochrane Library等中英文数据库,检索时间范围为2011-01-01/2023-10-31日。比较PBC与PRT治疗TN的疗效和并发症等指标。采用Review Manager 5.4软件分析研究的主要结局。结果本研究最终纳入文献18篇,其中随机对照试验(randomized controlled trial,RCT)8篇,病例对照研究10篇,纳入TN患者共3013例,均为三叉神经第Ⅱ、Ⅲ支受累。PRT术后治愈率(OR=0.74,95%CI:0.53~1.02,P=0.07)、有效率(OR=0.94,95%CI:0.72~1.22,P=0.62)及复发率(OR=0.68,95%CI:0.40~1.15,P=0.15)与PBC比较差异无统计学意义,但术后的两个常见并发症——面部触觉减退发生率和咬肌无力发生率,PRT低于PBC(OR=2.84,95%CI:1.32~6.09,P<0.01;OR=2.86,95%CI:1.55~5.25,P<0.01)。结论PRT在TN的疗效方面拥有优势,且主要并发症发生率更低,是临床上治疗TN的重要方式之一。
Objective To evaluate the efficacy of percutaneous balloon compression(PBC)and percutaneous radiofrequency thermocoagulation(PRT)in the treatment of trigeminal neuralgia(TN).Methods Chinese and Eng-lish databases such as China National Knowledge Infrastructure,Wanfang data,internet,PubMed,EMbase and Co-chrane Library were retrieved by computer from January 1,2011 to October 31,2023.The efficacy and complications of PBC and PRT in the treatment of TN were compared,and the main outcome of the study was analyzed by Review Man-ager 5.4 software.Results A total of 18 articles were included in this study,including 8 randomized controlled trial(RCT)and 10 case controlled studies,a total of 3013 patients with TN were involved inⅡandⅢbranches of the tri-geminal nerve.There was no significant difference in the cure rate(OR=0.74,95%CI:0.53-1.02,P=0.07),effective rate(OR=0.94,95%CI:0.72-1.22,P=0.62)and recurrence rate(OR=0.68,95%CI:0.40-1.15,P=0.15)PRT and PBC,however,the incidence rates of two common postoperative complications,facial hy-poesthesia and masseter muscle weakness,were lower in PRT than in PBC(OR=2.84,95%CI:1.32-6.09,P<0.01;OR=2.86,95%CI:1.55-5.25,P<0.01).Conclusion PRT has advantages in the efficacy of TN,and the incidence of major complications is lower,which is one of the important ways to treat TN clinically.
作者
李泓箭
何力兵
张川
杨汉丰
LI Hongjian;HE Libing;ZHANG Chuan;YANG Hanfeng(Radiology and Interventional Center,Affiliated Hospital of North Sichuan Medical College,Nanchong Sichuan 637000,China)
出处
《联勤军事医学》
CAS
2024年第3期250-257,共8页
Military Medicine of Joint Logistics
基金
国家临床重点专科建设项目(四川省卫计委医政函[2023]87号)
教育部产学合作协同育人项目2022年第二批立项项目(22097112074016)
南充市市校科技战略合作专项项目(9SXHZ0446)
南充市市校合作项目(22SXQT0029)。
关键词
三叉神经痛
经皮微球囊压迫术
经皮射频热凝术
疗效
并发症
Trigeminal neuralgia
Percutaneous balloon compression
Percutaneous radiofrequency thermocoagulation
Efficacy
Complication
