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洋甘菊的化学成分和药理作用研究进展及其质量标志物预测分析

Research Progress on Chemical Constituents and Pharmacological Effects of Matricaria chamomilia L.and Predictive Analysis of Quality Markers
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摘要 洋甘菊(Matricaria chamomilla L.)为菊科母菊属草本植物,是维吾尔医学常用药材,主产于中国新疆和欧洲等地。洋甘菊的化学成分主要包括黄酮、酚酸、挥发油、香豆素和其他类成分,具有抗炎、镇痛、抗菌、抗氧化、抗肿瘤、降血糖、降血脂、降血压和对胃肠道系统和神经系统的药理作用。本文在对洋甘菊化学成分、药理作用概述的基础上,对其质量标志物进行预测分析,推测黄酮、酚酸、倍半萜类成分可作为洋甘菊的质量标志物,为建立洋甘菊质量标准提供科学参考。 Matricaria chamomilla L.is a herbaceous plant belonging to Asteraceae family.It is frequently used as medicinal herb in the Uygur medicines and is mainly produced in Xinjiang Uygur autonomous region,Europe and other places.Its chemical constituents mainly include flavonoids,phenolic acids,essential oil,coumarins and other compounds.This herb has anti-inflammatory,analgesic,antibacterial,antioxidant,anti-tumor,hypoglycemic,hypolipidemic,hypotensive and pharmacological effects on gastrointestinal and nervous system.Based on the overview of the chemical constituents and pharmacological effects of chamomile,this paper conducts a predictive analysis of its quality markers.It is speculated that flavonoids,phenolic acids and sesquiterpenoids can be used as quality markers of chamomile,providing scientific reference for establishing its quality standards.
作者 李晶晶 陈少影 兰卫 LI Jingjing;CHEN Shaoying;LAN Wei(College of Traditional Chinese Medicine,Xinjiang Medical University,Urumqi 830017,China)
出处 《中国药学杂志》 CAS CSCD 北大核心 2024年第8期664-675,共12页 Chinese Pharmaceutical Journal
基金 国家自然科学基金地区科学基金项目资助(81960771) 新疆药学会科研基金项目资助(YXH202106)。
关键词 洋甘菊 黄酮 药理作用 质量标志物 Matricaria chamomilla L. flavonoid pharmacological activity quality marker
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