摘要
目的分析扶脾温肾汤对脾肾阳虚型患者口腔正畸治疗过程中牙槽骨变化、牙齿位移程度及龈沟液炎症因子的影响。方法回顾性收集2020年9月至2021年9月在山西省襄汾县人民医院进行口腔正畸治疗的脾肾阳虚型患者46例,分成2组,对照组(23例)予口腔正畸治疗(统一使用直丝弓固定矫正器),研究组(23例)在对照组基础上口服扶脾温肾汤。比较2组的牙槽骨变化、牙齿位移程度、牙周指标,以及龈沟液中白细胞介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)、前列腺素E2(PGE2)检测值。结果2组治疗前后牙槽骨厚度比较差异无统计学意义(P>0.05)。治疗后,研究组上、下颌弓宽较对照组大(P<0.05)。2组的菌斑指数(PLI)、牙龈指数(GI)以及龈沟液中IL-1β、TNF-α、PGE2检测值在治疗后较治疗前低(P<0.05),且研究组较对照组低(P<0.05),差异有统计学意义。结论扶脾温肾汤并未增加脾肾阳虚型患者口腔正畸治疗过程中牙槽骨厚度,但可促进牙齿位移,改善牙周状态,减轻炎性反应。
Objective To analyze the effects of Fupi Wenshen Decoction on alveolar bone changes,tooth displacement degree,and inflammatory factors in gingival crevicular fluid(GCF)during orthodontic treatment for patients with spleen-kidney yang deficiency syndrome.Methods A total of 46 patients with spleen-kidney yang deficiency syndrome who underwent orthodontic treatment at Xiangfen County People′s Hospital from September 2020 to September 2021 were included in the study.They were divided into two groups,the control group and the study group,according to different treatment methods.The control group(n=23)received orthodontic treatment(uniformly using straight wire archwire appliances),while the study group(n=23)received oral Fupi Wenshen Decoction treatment in addition to the same treatment as the control group.Comparisons were made between the two groups in terms of alveolar bone changes,tooth displacement degree,periodontal indicators,and the detection values of interleukin-1β(IL-1β),tumor necrosis factor-α(TNF-α),and prostaglandin E2(PGE2)in gingival crevicular fluid(GCF).Results For the same group,there was no significant difference in alveolar bone thickness between before and after treatment(P>0.05).After treatment,the maxillary and mandibular arch widths in the study group were larger than those in the control group(P<0.05).The plaque index(PLI),gingival index(GI),and the levels of IL-1β,TNF-α,and PGE2 in GCF were lower after treatment compared with before treatment(P<0.05),and they were lower in the study group than in the control group(P<0.05),the difference was statistically significant.Conclusion The Fupi Wenshen Decoction can not increase the thickness of alveolar bone in patients with spleen-kidney Yang deficiency during orthodontic treatment,but can promote tooth movement,improve periodontal status,and reduce inflammatory reactions.
作者
刘建勋
陕文芳
许宝珍
Liu Jianxun;Shan Wenfang;Xu Baozhen(Department of Stomatology,Xiangfen County People′s Hospital,Linfen,Shanxi 041500,China;Department of Traditional Chinese Medicine,Xiangfen County People′s Hospital,Linfen,Shanxi 041500,China)
出处
《中国药物与临床》
CAS
2024年第10期620-624,共5页
Chinese Remedies & Clinics
关键词
正畸学
牙槽骨质丢失
牙移位
扶脾温肾汤
Orthodontics
Alveolar bone loss
Tooth migration
Fupi Wenshen Decoction
