摘要
目的:探讨全病程多学科营养管理对食管癌放疗患者骨骼肌指数丢失值及放疗进程的影响。方法:选取2020年1月—2023年1月收治的食管癌放疗患者80例,采用随机数字表法分为观察组与对照组,每组40例。对照组给予常规饮食干预方案,观察组给予全病程多学科营养管理干预方案,随访至放疗后6个月,比较两组入院时和干预7 d后营养指标[身体质量指数(BMI)、血清白蛋白(ALB)、前白蛋白(PAB)],比较两组入院时和随访时的骨骼肌指数值(SMI)及各放疗期延迟时间。结果:两组入院时各项营养指标比较,差异无统计学意义(P>0.05)。两组入院时身体质量指数比较,差异无统计学意义(P>0.05);干预7 d后,身体质量指数与入院时比较,差异无统计学意义(P>0.05);干预7 d后两组ALB均低于入院时,但观察组明显高于对照组,差异有统计学意义(P<0.05);干预7 d后对照组PAB低于入院时,观察组PAB高于入院时,且观察组明显高于对照组(P<0.05);随访6个月后,两组SMI比较,随访时均低于入院时(P<0.05),且观察组高于对照组(P<0.05);观察组T0期、T1期、T2期放疗延迟时间均短于对照组(P<0.05)。结论:全病程多学科营养管理可显著改善食管癌放疗患者营养状况,降低SMI丢失,保证放疗的顺利进行。
Objective:To investigate the effects of multi-disciplinary nutrition management on skeletal muscle index loss and radiotherapy course in patients with esophageal cancer.Methods:A total of 80 patients treated with radiotherapy for esophageal cancer in hospital from January 2020 to January 2023 were selected and divided into study group and control group by simple random method using random number table.40 cases in each group.The control group was given the routine diet intervention program,the observation group was given the whole course of multi-disciplinary nutritional management intervention program.Follow-up was conducted until 6 months after radiotherapy.Nutritional indexes body mass index(BMI),serum albumin(ALB),prealbumin(PAB),skeletal muscle index(SMI)at admission and follow-up,delay time of each radiotherapy period were compared between the two groups at admission and 7 days after intervention,and adverse reactions were compared between the two groups at 6 months after radiotherapy.Results:There were no significant differences in various nutrition indexes between the two groups at admission(P>0.05).Weight after 7 days of intervention had no significant change compared with admission(P>0.05).ALB 7 days after invervention in both groups was lower than that at admission(P<0.05),the study group was significantly higher than that at admission(P<0.05).PAB 7 days after invervention in the control group was lower than that at admission,and that in the study group was higher than that at admission.The study group was significantly higher than the control group(P<0.05).At follow up,the weight of both groups was lower than that at dimission,and in the study group was lower than that in the control group(P<0.05).The delay time of T0,T1 and T2 radiotherapy in the study group was shorter than that in the control group(P<0.05).Conclusion:Multi-disciplinary nutrition management can significantly improve the nutritional status of patients with esophageal cancer and reduce the loss of skeletal muscle index,so as to ensure the smooth implementation of radiotherapy.
作者
王京丹
王露露
魏晓辉
WANG Jingdan;WANG Lulu;WEI Xiaohui(The First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471000,China)
出处
《临床医药实践》
2024年第7期553-556,共4页
Proceeding of Clinical Medicine
关键词
全病程多学科营养管理
食管癌
放疗
骨骼肌指数
放疗进程
multidisciplinary nutrition management throughout the course of disease
esophageal cancer
radiotherapy
skeletal muscle index
radiotherapy course
