摘要
目的:评估显微根尖手术对慢性根尖周炎(CAP)患者的影响。方法:选取2021年1月—2022年12月桂林市口腔医院收治的80例CAP患者,根据随机数表法将其分为对照组(40例)和观察组(40例)。对照组给予传统根尖外科手术,观察组给予显微根尖手术。比较两组手术效果,术后7 d疼痛情况,术前及术后3个月、6个月根尖周指数(PAI)评分,术前及术后4周龈沟液炎症因子,并发症。结果:观察组总有效率(95.00%)高于对照组(77.50%),差异有统计学意义(P<0.05)。术后7 d,观察组疼痛发生率(12.50%)低于对照组(40.00%),差异有统计学意义(P<0.05)。术后3个月、6个月,观察组PAI评分均低于对照组,差异有统计学意义(P<0.05)。术后4周,观察组肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)水平均低于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率(2.50%)低于对照组(15.00%),差异有统计学意义(P<0.05)。结论:CAP患者实施显微根尖手术,可以提高治疗效果,减轻炎症反应、疼痛感,减少术后并发症,改善根尖周情况。
Objective:To evaluate the effect of microscopic apical surgery on patients with chronic apical periodontitis(CAP).Method:A total of 80 patients with CAP who admitted to Guilin Stomatological Hospital from January 2021 to December 2022 were selected,they were divided into the control group(40 cases)and the observation group(40 cases)according to random number table method.The control group was given traditional apical surgery,and the observation group was given microscopic apical surgery.The surgical effect,pain condition at 7 d after surgery,periapical index(PAI)score before surgery and 3 months and 6 months after surgery,inflammatory factors in gingival crevicular fluid before surgery and 4 weeks after surgery,complications were compared between two groups.Result:The total effective rate of the observation group(95.00%)was higher than that of the control group(77.50%),and the difference was statistically significant(P<0.05).At 7 d after surgery,the incidence of pain in the observation group(12.50%)was lower than that in the control group(40.00%),and the difference was statistically significant(P<0.05).At 3 months and 6 months after surgery,the PAI scores in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).At 4 weeks after surgery,the levels of tumor necrosis factor-α(TNF-α),interleukin-1β(IL-1β)and interleukin-6(IL-6)in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).The incidence of complication of the observation group(2.50%)was lower than that of control group(15.00%),and the difference was statistically significant(P<0.05).Conclusion:Microscopic apical surgery for CAP patients can improve the therapeutic effect,reduce inflammation reaction and pain sensation,reduce postoperative complications,and improve periapical conditions.
作者
王路荣
WANG Lurong(Guilin Stomatological Hospital,Guilin 541000,China)
出处
《中外医学研究》
2024年第18期47-50,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
显微根尖手术
慢性根尖周炎
疼痛
龈沟液炎症因子
Microscopic apical surgery
Chronic apical periodontitis
Pain
Inflammatory factors in gingival crevicular fluid
