摘要
目的探讨常规超声联合超声造影在不规则乳腺结节良恶性鉴别中的应用价值。方法回顾性分析2021年12月至2022年12月于抚州市直属门诊部就诊的102例不规则乳腺结节患者的临床资料。患者均行超声造影、常规超声,以病理结果为金标准,比较良性与恶性患者常规超声联合超声造影特征,ROC曲线分析常规超声、超声造影鉴别诊断不规则乳房结节良恶性的诊断效能。结果102例不规则乳房结节患者,良性结节47例,恶性结节55例。其中良性结节包括腺病36例,浆细胞性乳腺炎5例,导管内乳头状瘤4例,纤维腺瘤2例;恶性结节包括浸润性导管癌20例,导管原位癌15例,原位癌伴微浸润13例,实性乳头状癌3例,弥漫性大B细胞淋巴瘤2例,浸润性小叶癌2例。良性患者与恶性患者微钙化、弹性、始增时间、增强强度、增强模式、增强后病变范围、周围血管征特征占比比较差异有统计学意义(P<0.05)。ROC曲线分析结果显示,常规超声联合超声造影灵敏度、特异度、准确度及AUC均高于常规超声、超声造影单一诊断。结论常规超声联合超声造影诊断评估不规则乳腺结节良恶性鉴别诊断具有较高的应用价值,可提升诊断不规则乳腺结节的准确度、灵敏度。
Objective To explore the application value of conventional ultrasound combined with contrast-enhanced ultrasound in the differential diagnosis of benign and malignant irregular breast nodules.Methods The clinical data of 102 patients with irregular breast nodules from December 2021 to December 2022 in our hospital were retrospectively analyzed.All patients underwent contrast-enhanced ultrasound and conventional ultra-sound,the pathological results were used as the gold standard,the characteristics of contrast-enhanced ultrasound combined with conventional ultra-sound in benign and malignant patients were compared,ROC curve was used to analyze the diagnostic efficacy of conventional ultrasound and con-trast-enhanced ultrasound in the differential diagnosis of benign and malignant irregular breast nodules.Results Among 102 patients with irregular breast nodules,47 were benign nodules and 55 were malignant nodules.Benign nodules included 36 cases of adenosis,5 cases of plasma cell mastitis,4 cases of intraductal papilloma and 2 cases of fibroadenoma,malignant nodules included 20 cases of invasive ductal carcinoma,15 cases of ductal car-cinoma in situ,13 cases of carcinoma in situ with microinvasion,3 cases of solid papillary carcinoma,2 cases of diffuse large B-cell lymphoma and 2 cases of invasive lobular carcinoma.There were statistically significant differences in the proportion of microcalcification,elasticity,initial en-hancement time,enhancement intensity,enhancement mode,lesion range after enhancement,and peripheral vascular sign characteristics between benign and malignant patients(P<0.05).The results of ROC curve analysis showed that the sensitivity,specificity,accuracy and AUC of conven-tional ultrasound combined with contrast-enhanced ultrasound were higher than those of conventional ultrasound and contrast-enhanced ultrasound.Conclusion Conventional ultrasound combined with contrast-enhanced ultrasound diagnosis has the high application value in the differential diagno-sis of benign and malignant irregular breast nodules,which can improve the accuracy and sensitivity of the diagnosis of irregular breast nodules.
作者
王芳
邹莉莉
潘晓珍
WANG Fang;ZOU Lili;PAN Xiaozhen(Department of Ultrasonography,Fuzhou Directly Affiliated Outpatient Department,Fuzhou,Jiangxi,344000,China)
出处
《当代医学》
2024年第8期96-99,共4页
Contemporary Medicine
关键词
常规超声
超声造影
不规则乳腺结节
良恶性
Conventional ultrasound
Contrast-enhanced ultrasound
Irregular breast nodules
Benign and malignant
