摘要
目的比较宫腔镜术前应用间苯三酚注射液、米索前列醇、一次性宫颈扩张用模具软化宫颈的效果及不良反应。方法选择2020年7月至2022年12月在该院进行宫腔镜手术的150例患者为研究对象,按照随机数字表法分为间苯三酚组(A组)、米索前列醇组(B组)、一次性宫颈扩张用模具组(C组),每组50例。比较3组患者宫颈软化效果、扩宫时间、术中漏水率及不良反应发生率。结果3组患者宫颈软化有效率比较,差异均有统计学意义(P=0.023),A组宫颈软化有效率明显高于B组(P=0.012),C组宫颈软化有效率虽高于B组,但差异无统计学意义(P=0.053)。3组患者扩宫时间比较,差异有统计学意义(P=0.018),A组和C组扩宫时间均短于B组,差异有统计学意义(P=0.008、0.031),A组和C组扩宫时间比较,差异无统计学意义(P=0.600)。3组患者术中漏水率比较,差异无统计学意义(P=0.108)。3组患者不良反应发生率比较,差异有统计学意义(P<0.001)。B组不良反应发生率最高,均明显高于A组与C组(P<0.001、0.011)。结论3种宫颈扩张方法各有利弊,宫腔镜术前需结合手术时间、漏水率、医疗成本、不良反应等综合考虑,选择软化宫颈的方式。
Objective To compare the efficacies and adverse reactions among phloroglucinol injection,misoprostol and disposable cervical dilation mold before hysteroscopy in softening the cervix.Methods A total of 150 patients undergoing hysteroscopic surgery in this hospital from July 2020 to December 2022 were selected and divided into the phloroglucinol group(group A),misoprostol group(group B)and disposable cervical dilation mold group(group C)according to the random number table method,50 cases in each group.The cervical softening effect,uterine dilation time,intraoperative water leakage rate and adverse reaction rate were compared among the three groups of patients.Results There was statistically significant difference in the effective rate of cervical softening among the three groups(P=0.023).The effective rate of cervical softening in the group A was significantly higher than that in the group B(P=0.012).Although the effective rate of cervical softening in the group C was higher than that in the group B,but the difference was not statistically significant(P=0.053).The uterine dilation time had statistically significant difference among the three groups(P=0.018).The uterine dilation time in the group A and group C was shorter than that in the group B,and the differences were statistically significant(P=0.008,0.031).The uterine dilation time had no statistically significant difference between the group A and group C(P=0.600).There was no statistically significant difference in the intraoperative water leakage rate among the three groups(P=0.108).The incidence rate of adverse reactions had statistically s ignificant difference among the three groups(P<0.001).The incidence rate of adverse reactions in the group B was the highest,which significantly higher than that in the group A and group C(P<0.001,0.011).Conclusion Each of the three methods of cervical dilation has advantages and disadvantages.Preoperative hysteroscopy should be combined with the length of operation,water leakage rate,medical cost and adverse reactions to comprehensively consider and select the cervical softening method.
作者
李永康
梁苗
温宇
陈诚
LI Yongkang;LIANG Miao;WEN Yu;CHEN Cheng(Department of Obstetrics and Gynecology,Chongqing Municipal People′s Hospital,Chongqing 401147,China)
出处
《检验医学与临床》
CAS
2024年第14期2016-2019,2024,共5页
Laboratory Medicine and Clinic
基金
重庆市技术创新与应用发展专项重点项目(CSTB2022TIAD-KPX0154、CSTB2022TIAD-KPX0183)
重庆市人民医院“五个一”人才计划项目(渝人院2023第47号)。
关键词
宫颈扩张用模具
间苯三酚注射液
米索前列醇
宫腔镜
宫颈软化
disposable cervical dilation mould
phloroglucinol injection
misoprostol
hysteroscopy
cervical softening
