摘要
目的 分析血液检测指标与ABO血型不合新生儿溶血病的关系及诊断价值。方法 收集2021年1月—2022年12月在德江县人民医院分娩的70例新生儿的临床资料。对新生儿静脉血进行红细胞抗体放散实验,通过洗涤、放散、离心,采用全自动血细胞分析仪分析产妇及新生儿的血液检测指标[包括总胆红素(TBil)、中性粒细胞比例(NEU%)、血红蛋白(Hb)、血小板计数(PLT)、直接胆红素(DBil)、平均红细胞体积(MCV)];比较ABO血型不合新生儿溶血病的诊断率以及患儿与正常新生儿的上述指标水平差异。结果 ABO血型不合新生儿溶血病的诊断率为8.57%(6/70);患儿的TBil和NEU%水平均显著高于正常新生儿,Hb水平显著低于正常新生儿[TBil(μmol/L):265.34±16.35比186.34±13.68;NEU%:(65.34±6.37)%比(53.62±5.69)%;Hb(g/L):133.67±16.62比175.65±20.68;均P<0.05];PLT、DBil、MCV与正常新生儿比较差异均无统计学意义[PLT(×10^(9)/L):265.62±18.62比265.37±18.67;DBil(μmol/L):19.32±4.32比18.99±3.96;MCV(fL):104.32±6.34比104.37±6.38;均P>0.05]。结论 血液检测中Hb、NEU%、MCV、TBil等指标与新生儿溶血病的患病情况有关,可作为疾病早期预测和诊断的重要依据。上述指标联合检测可进一步提高诊断的准确性,为临床及时治疗和干预提供有力支持。
Objective To analyze the relationship between ABO blood type incompatibility hemolytic disease in newborns and blood testing indicators and their diagnostic value.Methods The clinical data of 70 neonates delivered in Dejiang County People's Hospital from January 2021 to December 2022 were collected,and the erythrocyte antibody release test was performed on the neonatal venous blood,and the blood detection indexes[including total bilirubin(TBil),neutrophil ratio(NEU%),hemoglobin(Hb),platelet count(PLT),direct bilirubin(DBil)and mean corpuscular volume(MCV)]of mothers and neonates were analyzed by automatic blood cell analyzer.The diagnostic rate of ABO incompatibility neonatal hemolytic disease was summarized,and the blood testing indicators were compared with those of 70 normal neonates.Results The diagnostic rate of ABO incompatibility neonatal hemolytic disease was 8.57%(6/70).The levels of TBil and NEU%of patients were significantly higher than those of normal newborns,and the level of Hb was significantly lower than that of normal newborns[TBil(μmol/L):265.34±16.35 vs.186.34±13.68;NEU%:(65.34±6.37)%vs.(53.62±5.69)%;Hb(g/L):133.67±16.62 vs.175.65±20.68;all P<0.05].There was no statistically significant difference in the levels of PLT,DBil and MCV compared to normal newborns[PLT(×10^(9)/L):265.62±18.62 vs.265.37±18.67;DBil(μmol/L):19.32±4.32 vs.18.99±3.96;MCV(fL):104.32±6.34 vs.104.37±6.38;all P>0.05].Conclusions Indicators such as Hb,NEU%,MCV and TBil in blood tests are related to the incidence of HDN and could serve as important criteria for early prediction and diagnosis.The combined detection of above indicators could further improve the accuracy of diagnosis,providing strong support for timely clinical treatment and intervention.
作者
陈梅
王琳燕
Chen Mei;Wang Linyan(Department of Blood Transfusion,Dejiang County People's Hospital,Tongren 565200,Guizhou,China)
出处
《实用检验医师杂志》
2024年第2期162-165,共4页
Chinese Journal of Clinical Pathologist
关键词
总胆红素
直接胆红素
血液检测指标
ABO血型不合新生儿溶血病
Total bilirubin
Direct bilirubin
Blood testing indicator
ABO blood type incompatibility hemolytic disease of newborn
