摘要
目的研究细支气管腺瘤的临床及胸部CT影像学表现。方法纳入2016—2021年临沂市人民医院及烟台毓璜顶医院经手术病理确诊为细支气管腺瘤的患者,回顾性分析其临床及CT影像学特征。结果纳入患者25例,其中男6例、女19例,年龄32~73(58.6±10.1)岁。所有病变免疫组织化学显示核增殖抗原Ki67(MIB1)均<5%。病变位于双肺上中叶9例,双肺下叶16例;位于肺外带22例,肺内中带3例;病变类圆形11例,不规则形14例;边界清楚22例;纯磨玻璃/混合磨玻璃结节6例,实性结节19例;有中心小空洞11例;有单支细支气管血管连接征18例;与邻近胸膜无粘连19例;无纵隔淋巴结肿大24例。结论细支气管腺瘤好发于中老年人,多发生于双肺下叶、外周肺野,患者多无任何临床症状,术后预后良好;CT上可表现较大结节或肿块、纯磨玻璃/混合磨玻璃结节、不规则实性小结节、中心小空洞。形态不规则的星芒样小结节、中心小空洞影、单支细支气管血管束与病变相连为细支气管腺瘤相对特异的影像学表现。
Objective To study the clinical and CT findings of bronchiolar adenoma.Methods Patients diagnosed with bronchiolar adenoma confirmed by surgical pathology at Linyi People's Hospital and Yantai Yuhuangding Hospital from 2016 to 2021 were collected.Their clinical and CT imaging features were retrospectively analyzed.Results Finally,25 patients were collected,including 6 males and 19 females,aged 32-73(58.6±10.1)years.The immunohistochemical Ki-67(MIB1)of all lesions was<5%.The lesions were located in the upper and middle lobe of both lungs in 9 patients,lower lobes in 16 patients,extrapulmonary zone in 22 patients,intrapulmonary middle zone in 3 patients,round in 11 patients,irregular in 14 patients,well-defined in 22 patients,pure ground-glass/mixed ground-glass nodules in 6 patients,solid nodules in 19 patients.There were 11 patients with central small cavity,18 patients with single bronchioles sign,19 patients without adhesion with adjacent pleura,and 24 patients without mediastinal lymph node enlargement.Conclusion Bronchiolar adenomas usually occur in the middle-aged and elderly,mostly in the lower lobe of both lungs and the distribution of the peripheral lung field,most of the patients do not have any clinical symptoms,and the postoperative prognosis is good.CT may show large nodules or masses,pure ground-glass/mixed ground-glass nodules,irregular solid nodules and central small cavities.Irregular stellate nodules,central small cavity shadow,and single bronchiolar vascular bundle connected with the lesions are relatively specific imaging findings of bronchiolar adenoma.
作者
张明辉
隋洺骅
邱甜甜
孙雪
谭晓
侯代伦
ZHANG Minghui;SUI Minghua;QIU Tiantian;SUN Xue;TAN Xiao;HOU Dailun(Department of Medical Imaging,Linyi People’s Hospital,Linyi,276005,Shandong,P.R.China;Department of Oncology,Yantai Yuhuangding Hosptial,Qingdao University,Yantai,264000,Shandong,P.R.China;Department of Pathology,Linyi People’s Hospital,Linyi,276005,Shandong,P.R.China;Department of Medical Imaging,Beijing Chest Hospital,Capital Medical University,Beijing,101149,P.R.China)
出处
《中国胸心血管外科临床杂志》
CSCD
北大核心
2024年第8期1127-1132,共6页
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
基金
山东省医药卫生科技发展计划项目(202209011113)。
