摘要
因生活和工作压力所引起的心烦失眠已严重影响到现代人的身心健康,并诱发诸多疾病。养心安神类中药质量稳定,对治疗失眠疗效显著,不良反应较少,且无镇静催眠类化学药的依赖性。养心安神类中药饮片及制剂按其功能可分为养心安神药和重镇安神药,其活性成分主要有黄酮类、生物碱类、有机酸类、多糖类、氨基酸类和维生素类等,临床多用于心血管疾病治疗和中枢神经抑制。本文对其种类、有效成分、发展趋势及其临床应用现状进行综述,以期为养心安神类药物在临床应用及相关药物的研发提供参考。
The upset insomnia caused by life and work pressure has seriously affected the physical and mental health of modern people and induced many diseases.The quality of Chinese medicine for nourishing heart and tranquilizing mind is stable,and it has a significant effect on the treatment of insomnia,with fewer adverse reactions,and no dependence on sedative and hypnotic as chemical drugs.The Chinese herbal pieces and preparations for nourishing heart and tranquilizing mind can be divided into psychotropic and sedative drugs according to their functions.Their active ingredients mainly include flavonoids,alkaloids,organic acids,polysaccharides,amino acids and vitamins,etc.They are mostly used in the treatment of cardiovascular diseases and central nervous system inhibition.In this paper,the types and active ingredients and development tendency and application status of the Chinese herbal pieces and preparations of nourishing heart and tranquilizing mind were reviewed individually,in order to provide reference for the development of drugs of nourishing heart and tranquilizing mind in the field of clinical application and related drugs.
作者
冯佳锐
凃鑫
张宜仲
田琦
黄丽思
刘立丽
鲍康德
王丹
FENG Jiarui;TU Xin;ZHANG Yizhong;TIAN Qi;WONG LISOO;LIU Lili;BAO Kangde;WANG Dan(School of Life Science and Medicine,Zhejiang Sci-Tech University,Hangzhou 310018,China;Zhejiang Key Laboratory of Silkworm Bioreactor and Biomedicine,Hangzhou 310063,China;Pharmaceutical Research Institute of Zhejiang Guobang Pharmaceutical Co.,Ltd.,Shaoxing 312369,China)
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2024年第13期1853-1863,共11页
Chinese Journal of Modern Applied Pharmacy
基金
浙江理工大学绍兴生物医药研究院开放基金项目(SXAB202216)
科技横向“食药物质提取工艺、质量标准及小试生产研究”(22040252-J)。
关键词
养心安神
中药饮片
中药制剂
临床应用
nourishing heart and tranquilizing mind
Chinese herbal pieces
traditional Chinese medicine preparations
clinical application
