摘要
目的:运用数据挖掘方法,对明清时期中医古籍中治疗妊娠恶阻的方剂进行整理、分析,挖掘其中的用药规律。方法:收集明清时期中医古籍中治疗妊娠恶阻的方剂,经筛选处理后录入中医传承辅助平台(V2.5),建立中药处方数据库,通过软件集成算法,明晰核心用药,总结辨治规律。结果:共纳入方剂93首,涉及中药81味,其中出现频次较高的中药有茯苓、人参、生姜、陈皮、半夏、白术、甘草等,药性以温性为主,药味以辛、甘、苦居多,多归脾、肺、胃三经,高频中药的关联规则分析共得到药物组合28组,聚类分析得到潜在处方4首。结论:明清时期治疗妊娠恶阻从“脾、肺、胃”入手,用药以温为主,药味以辛、甘、苦居多,治法以补中益气、燥湿化痰为主,用药具有一定的特色,可为现代中医药临床治疗妊娠恶阻提供参考。
Objective:To use data mining methods to sort out and analyze the prescriptions for treating nausea and vomiting during pregnancy in ancient Chinese medical books during the Ming and Qing Dynasties,and to explore the drug usage rules.Methods:The prescriptions for treating nausea and vomiting during pregnancy in ancient Chinese medical books during the Ming and Qing Dynasties were collected and entered into the Chinese medicine inheritance auxiliary platform(V2.5)after screening and processing.A Chinese medicine prescription database was established.The core drugs were clarified and the rules of diagnosis and treatment were summarized through the software integra-tion algorithm.Results:A total of 93 prescriptions were included,involving 81 Chinese medicines.Among them,the Chinese medicines with higher frequency of occurrence included Poria cocos,ginseng,ginger,tangerine peel,Pinellia tuber,Atractylodes macrocephala,and Licorice.The medicinal properties were mainly warm,and the medicinal flavors were mostly pungent,sweet,and bitter.Most of them belonged to the spleen,lung,and stomach meridians.The associa-tion rule analysis of high-frequency Chinese medicines obtained a total of 28 drug combinations,and cluster analysis obtained 4 potential prescriptions.Conclusion:Treatment of nausea and vomiting during pregnancy in the Ming and Qing Dynasties started with the spleen,lungs,and stomach.The drugs used were mainly warm,and the taste of the drugs was mostly pungent,sweet,and bitter.The treatment method was mainly to tonify the middle and replenish Qi,and to dry dampness and resolve phlegm.The drugs used had certain characteristics and could provide a reference for the modern clinical treatment of nausea and vomiting during pregnancy with traditional Chinese medicine.
作者
彭心蕾
程红
PENG Xinlei;CHENG Hong(Anhui University of Chinese Medicine,Anhui Hefei 230038,China;The First Affiliated Hospital of Anhui University of Chinese Medicine,Anhui Hefei 230031,China)
出处
《中医药临床杂志》
2024年第8期1530-1534,共5页
Clinical Journal of Traditional Chinese Medicine
基金
省级研究生教育教学改革研究项目(NO.2022jyjxggyj303)
安徽省重点研究与开发计划项目(NO.202204295107020041)。
关键词
妊娠恶阻
用药规律
明清时期
中医古籍
中医传承辅助平台
Nausea and vomiting during pregnancy
Drug use rules
Ming and Qing dynasties
Ancient Chinese medicine books
Auxiliary platform for the inheritance of traditional Chinese medicine
