摘要
目的:观察大承气汤保留灌肠联合甘遂末内服治疗对急性胰腺炎患者的疗效。方法:选取2022年2月—2023年7月就诊的68例急性胰腺炎患者为研究对象,分为两组,每组34例。对照组为西医常规治疗方案,观察组在对照组基础上应用大承气汤保留灌肠联合甘遂末内服治疗。两组均完成1个疗程(5 d)的治疗,比较两种治疗方式治疗前后的实验室指标、临床症状及影像学结果等,从而评价相应的临床效果。结果:治疗后,观察组的有效率高于对照组(97.1%vs 73.5%,P<0.05)。治疗后,观察组患者的排气恢复时间及腹痛缓解时间均短于对照组(P<0.05);观察组患者的腹痛、腹胀及改良的CT严重指数评分均优于对照组(P<0.05);两组患者的白细胞计数、血淀粉酶、血脂肪酶以及肝功能指标(ALT、AST)水平均降低,观察组的改善程度均优于对照组(P<0.05)。结论:大承气汤保留灌肠联合甘遂末内服治疗急性胰腺炎患者的临床疗效显著,可加快症状、体征的恢复,减轻炎症反应,对肝功能的改善具有一定作用,值得临床推广。
Objective:To investigate the clinical therapeutic effect of Dachengqi Decoction retention enema combined with Gansui powder taken orally in patients with acute pancreatitis.Methods:A total of 68 patients with acute pancreatitis from February 2022 to July 2023 were divided into two groups.The control group was treated with Western medicine treatment,and the experimental group was treated with Dachengqi Decoction retention enema combined with Gansui powder taken orally based on the control group.Both groups of patients were treated for a course of treatment(five days),and various observation indexes of two groups before and after treatment were analyzed to evaluate clinical efficacy,such as biochemical indexes,clinical symptoms and imaging results,etc.Results:The effective rate of the experimental group was higher than the control group(97.1%vs 73.5%,P<0.05).After treatment,the relief time for exhaust and abdominal pain in the experimental group was shorter than the control group(P<0.05);the degree of abdominal pain,abdominal distension,and modified CT severity index in the experimental group was better than the control group(P<0.05);the white blood cell count,blood amylase,blood lipase,and liver function indexes(ALT,AST)levels were all reduced,in which the degree of improvement in the experimental group was better than the control group(P<0.05).Conclusion:The clinical efficacy of Dachengqi Decoction retention enema combined with Gansui powder taken orally in the treatment of patients with acute pancreatitis is remarkable,accelerating the recovery of symptoms and signs,reducing the inflammatory response,and having a certain effect on the improvement of liver function,which is worthy of clinical promotion.
作者
廖淳
樊倩红
骆昱煜
李彩琴
伍预
LIAO Chun;FAN Qianhong;LUO Yuyu;LI Caiqin;WU Yu(Department of SurgeryⅠandⅡ,Zhuhai Hospital of Guangdong Provincial Hospital of Traditional Chinese Medicine,Zhuhai,Guangdong,519015,China;Department of Hepatobiliary Sur gery,the Fifth Affiliated Hospital of Sun Yat-sen University)
出处
《中国中西医结合消化杂志》
CAS
2024年第8期711-715,共5页
Chinese Journal of Integrated Traditional and Western Medicine on Digestion
关键词
大承气汤
保留灌肠
甘遂末
急性胰腺炎
Dachengqi Decoction
retention enema
Gansui powder
acute pancreatitis
