摘要
Electrical phenomena play an important role in numerous biological processes including cellular signaling,early embryogenesis,tissue repair and remodeling,and growth of organisms.Electrical and magnetic effects have been studied on a variety of stimulation strategies and cell types regarding cellular functions and disease treatments.In this review,we discuss recent advances in using three different stimulation strategies,namely electrical stimulation via conductive and piezoelectric materials as well as magnetic stimulation via magnetic materials,to modulate cell and tissue properties.These three strategies offer distinct stimulation routes given specific material characteristics.This review will evaluate material properties and biological response for these stimulation strategies with respect to their potential applications in neural and musculoskeletal research.
基金
supported by the Technology and Research Initiative Fund(TRIF)from the University of Arizona
funding from the Alliance for Regenerative Rehabilitation Research&Training(AR3T)
supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development(NICHD)and the National Institute of Biomedical Imaging and Bioengineering(NIBIB)of the National Institutes of Health under Award Number P2CHD086843.
