摘要
目的探究高原地区青年罹患ST段抬高型心肌梗死(STEMI)的情况及危险因素。方法回顾性对青海省心脑血管病专科医院青年受试者的临床资料进行分析,根据STEMI观察情况分为观察组(60例)和正常组(60例),经倾向性匹配评分法(卡钳值为0.1),以1∶1匹配观察组及正常组,平衡两组间的混杂偏倚,收集并统计患者的临床资料,对影响青年罹患STEMI的因素进行单因素及多元线性回归分析。结果与正常组受试者相比,观察组合并糖尿病、有吸烟史、总胆固醇(TC)≥5.20 mmol/L、低密度脂蛋白胆固醇(LDL-C)≥3.40 mmol/L、直接胆红素(DB)≥6.8μmol/L、超敏C反应蛋白(hs-CRP)≥10 mg/L的人数更多(P<0.05);Logistic分析结果显示,合并糖尿病、有吸烟史、TC≥5.20 mmol/L、LDL-C≥3.40 mmol/L、DB≥6.8μmol/L、hs-CRP≥10 mg/L水平是影响高原地区青年群体患STEMI的独立危险因素(P<0.05)。结论在高原地区的青年人群中,糖尿病、吸烟史、TC、LDL-C、DB以及hs-CRP水平是罹患STEMI的独立危险因素,针对性进行预防措施,加强患者基础疾病治疗,对降低STEMI患病风险有重要意义。
Objective To explore the status and risk factors of ST-segment elevation myocardial infarction(STEMI)in young people in plateau area.Methods The clinical data of young subjects in Qinghai Province Cardiovascular and Cerebrovascular Specialist Hospital were retrospectively analyzed.According to the prevalence status of STEMI,they were divided into observation group(60 cases)and normal group(60 cases).The propensity score matching method(caliper=0.1)was used to match the observation group and the normal group at 1∶1,and the confounding biases between the two groups were balanced.The clinical data of the patients were collected and counted,and the factors affecting the young patients with STEMI were analyzed by univariate analysis and multivariate linear regression analysis.Results Compared with the normal group,the number of patients with diabetes mellitus,smoking history,total cholesterol(TC)≥5.20 mmol/L,low-density lipoprotein cholesterol(LDL-C)≥3.40 mmol/L,direct bilirubin(DB)≥6.8μmol/L and high sensitivity C-reactive protein ks-CRP≥10 mg/L in the observation group was more(P<0.05).Logistic analysis showed that diabetes mellitus,smoking history,TC≥5.20 mmol/L,LDL-C≥3.40 mmol/L,DB≥6.8μmol/L and hs-CRP≥10 mg/L were independent risk factors for STEMI in young people in plateau area(P<0.05).Conclusion Diabetes mellitus,smoking history,TC,LDL-C,DB and hs-CRP are independent risk factors for STEMI in young people in plateau area.Targeted preventive measures and improved management of underlying diseases in patients are of significant and importance in reducing the risk of STEMI.
作者
赵文兴
童有福
曹建东
贾蕾
胡婷婷
ZHAO Wenxing;TONG Youfu;CAO Jiandong;JIA Lei;HU Tingting(Interventional Center,Qinghai Specialized Hospital for Cardiovascular and Cerebrovascular Diseases,Xining Qinghai 810012,China)
出处
《中国急救复苏与灾害医学杂志》
2024年第9期1193-1196,共4页
China Journal of Emergency Resuscitation and Disaster Medicine
基金
青海省卫健委课题(编号:2023-wjzdx-56)。
关键词
ST段抬高型心肌梗死
高原地区
青年
发病率
危险因素
ST-segment elevation myocardial infarction
Plateau area
Young
Incidence rate
Risk factors
