摘要
目的 探讨双参数磁共振成像(BP-MRI)联合前列腺特异性抗原(PSA)指标诊断前列腺癌的价值。方法 选取疑似前列腺癌患者86例作为研究对象,分别接受BP-MRI检查及PSA指标检查。以病理诊断结果作为金标准,记录BP-MRI、PSA指标单独检查及联合检查诊断前列腺癌的结果 ,对比三种检查方法的诊断效能;对比前列腺癌与前列腺增生患者PSA指标[游离前列腺特异性抗原(f-PSA)、总前列腺特异性抗原(t-PSA)]。结果 86例疑似前列腺癌患者经病理诊断, 45例(52.33%)确诊为前列腺癌, 41例(47.67%)确诊为前列腺增生。BP-MRI单独检查阳性38例,阴性48例;PSA指标单独检查阳性40例,阴性46例;联合检查阳性46例,阴性40例。联合检查的诊断灵敏度97.78%、准确率96.51%均明显高于BP-MRI单独检查的80.00%、87.21%和PSA指标单独检查的82.22%、87.21%(P<0.05)。前列腺癌患者f-PSA(5.81±1.96)ng/ml、t-PSA(38.52±5.65)ng/ml均明显高于前列腺增生患者的(1.85±0.31)、(8.22±1.68)ng/ml(P<0.05)。结论 临床诊断前列腺癌时可采取BP-MRI联合PSA指标的方式,相比单一检查准确性更高,可为临床提供可靠影像及指标支持,值得推广。
Objective To explore the diagnostic value of biparametric magnetic resonance imaging(BP-MRI)combined with prostate specific antigen(PSA)markers for prostate cancer.Methods 86 patients with suspected prostate cancer were selected as the study subjects,and all underwent BP-MRI and PSA examination respectively.The pathological diagnosis results were used as the gold standard,and the results of BP-MRI and PSA alone and in combination were recorded for the diagnosis of prostate cancer,and the diagnostic efficacy of the three examination methods was compared;the PSA parameters[free prostate-specific antigen(f-PSA),total prostate-specific antigen(t-PSA)]were compared between patients with prostate cancer and those with prostate hyperplasia.Results 86 suspected prostate cancer patients were diagnosed by pathology,of which 45 cases(52.33%)were diagnosed with prostate cancer,and 41 cases(47.67%)were diagnosed with prostate hyperplasia.BP-MRI alone was positive in 38 cases and negative in 48 cases;PSA parameters alone was positive in 40 cases and negative in 46 cases;and combined examination was positive in 46 cases and negative in 40 cases.The diagnostic sensitivity and accuracy of the combined examination were 97.78%and 96.51%,which were significantly higher than 80.00%and 87.21%of BP-MRI examination alone,and 82.22%and 87.21%of PSA parameters examination alone(P<0.05).The f-PSA of prostate cancer patients was(5.81±1.96)ng/ml and t-PSA was(38.52±5.65)ng/ml,which were significantly higher than(1.85±0.31)and(8.22±1.68)ng/ml of prostate hyperplasia patients(P<0.05).Conclusion The clinical diagnosis of prostate cancer can adopt the combination of BP-MRI and PSA parameters,which has higher accuracy compared to a single examination,and can provide reliable imaging and indicator support for clinical practice.It is worth promoting.
作者
殷海燕
YIN Hai-yan(Imaging Department,Haimen District Hospital of Traditional Chinese Medicine,Nantong 226100,China)
出处
《中国实用医药》
2024年第19期81-84,共4页
China Practical Medicine
关键词
双参数磁共振成像
前列腺特异性抗原指标
前列腺癌
前列腺增生
Biparametric magnetic resonance imaging
Prostate specific antigen markers
Prostate cancer
Prostatic hyperplasia
