摘要
目的 对比常规透析和高通量透析治疗慢性肾衰竭尿毒症期的疗效。方法 非随机选取涟水县中医院于2020年4月—2022年9月期间治疗的72例慢性肾衰竭尿毒症期患者为研究对象,以治疗方法不同分为观察组和参照组,各36例,参照组常规透析,观察组高通量透析,对比两组肾功能、免疫球蛋白水平和疗效。结果观察组患者的血尿酸、甲状旁腺激素、血肌酐、β_2微球蛋白指标均优于参照组,差异有统计学意义(P均<0.05);观察组患者的免疫球蛋白A、免疫球蛋白G、免疫球蛋白M水平均优于参照组,差异有统计学意义(P均<0.05);观察组疗效为97.22%(35/36),高于参照组的77.78%(28/36),差异有统计学意义(χ^(2)=4.571,P<0.05)。结论 慢性肾衰竭尿毒症期患者采用高通量透析产生的临床疗效更好。
Objective To compare the clinical efficacy of routine dialysis and high-throughput dialysis in chronic re-nal failure uremia.Methods A total of seventy-two chronic renal failure uremia patients treated in Lianshui County Hospital from April 2020 to September 2022 were non-randomly selected as a research object,and divided into obser-vation group and reference group with thirty-six cases in each group by different treatment.The reference group re-ceived routine dialysis treatment,and the observation group received high-throughput dialysis treatment.The renal function indexes,immunoglobulin levels and clinical efficacy of the two groups were compared.Results Serum acid,parathone,creatinine andβ2 microglobulin indexes in observation group were better than those in the reference group,the differences were statistically significant(all P<0.05).The levels of IgA,IgG and IgM in observation group were bet-ter than those in the reference group,the differences were statistically significant(all P<0.05).The clinical efficacy of observation group was 97.22%(35/36),higher than 77.78%(28/36)in the reference group,the difference was statisti-cally significant(χ^(2)=4.571,P<0.05).Conclusion High throughput dialysis with hemodialysis machine has better clini-cal effect on chronic renal failure uremia patients.
作者
蒯巧林
KUAI Qiaolin(Department of Nephrology,Lianshui Hospital of Traditional Chinese Medicine,Huaian 223400,Jiangsu,China)
出处
《系统医学》
2024年第15期74-76,80,共4页
Systems Medicine
关键词
血液透析机高通量透析
常规透析
慢性肾衰竭
尿毒症
Hemodialysis machine high throughput dialysis
Routine dialysis
Chronic kidney failure
Uremia
