摘要
门静脉血栓形成(PVT)是肝硬化的一种并发症,其发病率与肝硬化的严重程度呈正相关。一些与PVT发生和进展有关的危险因素已被发现,虽然完整的PVT对肝移植受者手术结果的负面影响已很清楚,但其对肝硬化进展的影响仍不确定。PVT治疗方案主要包括抗凝药物和介入溶栓治疗,需要根据每例患者血栓的特性作具体选择。本文总结了目前关于肝硬化非肿瘤性PVT的定义、流行病学、病理生理学、分级、危险因素、诊断、自然病史、临床后果和治疗方面的进展情况。
Portal vein thrombosis(PVT)is a complication of cirrhosis,and its incidence rate is positively correlated with the severity of cirrhosis.Some risk factors related to the occurrence and progression of PVT have been identified.Although the negative impact of fully formed PVT on the surgical outcomes of liver transplant recipients is clear,its impact on the progression of cirrhosis is still uncertain.The PVT treatment plan mainly includes anticoagulants and interventional thrombolysis,which requires specific selection based on the characteristics of each patient’s thrombus.This article summarizes the current progress in the definition,epidemiology,pathophysiology,grading,risk factors,diagnosis,natural history,clinical outcomes,and treatment of non-tumor PVT in liver cirrhosis.
作者
叶美妮
刘思嘉
臧玉玮
刘云建
Ye Meini;Liu Sijia;Zang Yuwei;Liu Yunjian(Department of Operating Theatre,Jiujiang University Affiliated Hospital,Jiujiang 332001,China;Department of Anesthesiology,Jiujiang University Affiliated Hospital,Jiujiang 332001,China;Archives of Jiujiang University,Jiujiang 332000,China;Department of Hepatobiliary Surgery,Jiujiang University Affiliated Hospital,Jiujiang 332001,China)
出处
《中华普通外科学文献（电子版）》
CAS
2024年第5期379-384,共6页
Chinese Archives of General Surgery(Electronic Edition)
基金
江西省自然科学基金面上项目(20202BABL206092)
江西省教育厅科学技术研究项目(GJJ161064)。
关键词
肝脏硬化
凝血障碍
门静脉高压
门静脉血栓
经颈静脉肝内门体分流术
Liver cirrhosis
Coagulation disorders
Portal hypertension
Portal vein thrombosis
Transjugular intrahepatic portosystemic shunt
