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机器人辅助胰腺钩突部肿瘤局部切除术16例临床分析

The outcomes of robotic-assisted enucleation for tumors located in uncinate process of pancreas in 16 cases
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摘要 目的总结机器人辅助胰腺钩突部肿瘤局部切除术的经验和手术技巧。方法本研究为回顾性病例系列研究。回顾性分析2019年6月至2023年12月浙江省人民医院胃肠胰外科收治的接受机器人辅助胰腺钩突部肿瘤局部切除术的16例患者的临床资料。男性10例,女性6例;年龄[M(IQR)]56(21)岁(范围:28~77岁);体重指数22.4(2.3)kg/m^(2)(范围:19.8~25.6 kg/m^(2))。术后3个月首次随访,之后6~12个月门诊随访一次,门诊随访延迟者通过电话随访。结果11例行钩突部肿瘤剜除术,5例行钩突切除术。患者的手术时间为70(60)min(范围:40~165 min),术中出血量30(13)ml(范围:10~80 ml)。术后胰瘘发生率为5/16。术后住院时间8(6)d(范围:5~33 d)。术后病理学检查结果显示,无功能神经内分泌肿瘤3例,胰岛素瘤2例,导管内乳头状黏液瘤5例,实性假乳头状瘤2例,黏液性囊腺瘤1例,浆液性囊腺瘤2例,假性囊肿1例。随访截至2024年3月12日,术后随访时间16(12)个月(范围:3~41个月)。所有患者无新发糖尿病,无消化不良。结论机器人手术辅助系统可用于胰腺钩突部肿瘤局部切除术,患者生活质量可。 Objective To summarize the experience of robot-assisted enucleation of tumors located in uncinate process of pancreas.Methods This is a retrospective case series study.The clinical data of patients with robot-assisted enucleation of tumors located in the uncinate process of pancreas at the Department of Gastroenterology and Pancreatic Surgery,Zhejiang Provincial People′s Hospital from June 2019 to December 2023 were retrospectively analyzed.A total of 16 cases were enrolled,including 10 males and 6 females,with an age(M(IQR))of 56(21)years(range:28 to 77 years),and body mass index of 22.4(2.3)kg/m^(2)(range:19.8 to 25.6 kg/m^(2)).Follow-up was asked every 6 to 12 months after the first 3-month postoperative follow-up through out-patient service or via telephone.Results In total 16 cases,there were 11 cases with pancreatic enucleation,and 5 cases with resection of the uninate process.The operation time was 70(60)minutes(range:40 to 165 minutes),and the blood loss was 30(13)ml(range:10 to 80 ml).The rate of pancreatic fistula was 5/16.The length of stay was 8(6)days(range:5 to 33 days).The pathological finding included non-functional neuroendocrine tumor(n=3),insulinoma(n=2),introductal papillary mucinous neoplasm(n=5),solid pseudopapillary neoplasm(n=2),mucinous cystadenoma(n=1),serous cystadenoma(n=2),pseudocyst(n=1).Follow-up as of March 12,2024,the follow-up time was 16(12)months(range:3 to 41 months).All patients had no new onset diabetes and no dyspepsia.Conclusion Robot-assisted surgical system can be used for local resection of uncinate process tumors of pancreas,and the quality of life of patients can be improved.
作者 金巍巍 路回正 陈景涛 朱启聪 鲁超 王元宇 牟一平 Jin Weiwei;Lu Huizheng;Chen Jingtao;Zhu Qicong;Lu Chao;Wang Yuanyu;Mou Yiping(Department of Gastroenterology and Pancreatic Surgery,Zhejiang Provincial People′s Hospital(People′s Hospital of Hangzhou Medical College),Key Laboratory of Gastroenterology of Zhejiang Province,Hangzhou 310014,China;The Second Clinical Medical College,Zhejiang Chinese Medical University,Hangzhou 310014,China;Postgraduate Training Base Alliance of Wenzhou Medical University,Hanghzou 310014,China)
出处 《中华外科杂志》 CAS CSCD 北大核心 2024年第10期923-928,共6页 Chinese Journal of Surgery
基金 国家卫生健康委科学研究基金-浙江省卫生健康重大科技计划(WKJ-ZJ-2201) 浙江省科技厅“领雁”计划重大社会公益项目(2022C03099)。
关键词 胰腺肿瘤 外科手术 胰腺钩突 肿瘤局部切除术 机器人 Pancreatic neoplasms Surgical procedures,operative Uncinate process of pancreas Local tumor resection surgery Robotics
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