摘要
Extrusion-based 3D bioprinting techniques are revolutionizing bioengineering by facilitating the creation of com-plex 3D microstructures.This review offers a thorough overview of extrusion-based 3D bioprinting methods,par-ticularly highlighting the innovative electric-assisted coil-write 3D bioprinting technology.The review begins by explicating the fundamental principles underlying various extrusion-based 3D bioprinting technologies.It covers the printing equipment composition,suitable materials for 3D bioprinting,and the latest breakthroughs in tech-nology.A critical aspect of this review is the in-depth comparison of the strengths and weaknesses associated with each 3D bioprinting approach.The electro-microfluidic extrusion method and the electric-assisted coil-write 3D bioprinting technology are highlighted.This advanced technology successfully overcomes the limitations of conventional extrusion-based methods,notably in the precise printing of intricately curved line structures with high resolution and speed.This method ingeniously integrates mechanical motion for creating microscale features with electrical coiling for sub-micron details,thus achieving remarkable printing speeds and structural complex-ity.This review concludes by exploring the potential applications and future advancements of this state-of-the-art technology.It underscores the ability of electric-assisted coil-write 3D bioprinting to develop pioneering materials and micro-devices for a variety of technological sectors,highlighting its transformative impact in bioengineering.
基金
the National Natural Science Foundation of China(NSFC 22308219,22078197,52172283)
the Guangdong Basic and Applied Basic Research Foundation(Grant No.2022A1515110246,2023A1515011827)
the Shenzhen Science and Technology Progra(JCYJ20220818095801003,RCYX20221008092902010)
the Shenzhen Natural Science Fund(the Stable Support Plan Program 20220810120421001)
the Medical-Engineering Interdisciplinary Research Foundation of Shenzhen University.
