摘要
目的探讨经皮穴位电刺激联合根管治疗对急性牙髓炎的影响。方法前瞻性研究,选取2023年4月至2024年4月在西安市第三医院口腔科治疗的102例急性牙髓炎患者作为研究对象,采用随机抽样法将其分为对照组(51例)和观察组(51例)。对照组男29例、女22例,年龄(40.57±2.16)岁,病程(1.59±0.50)年,接受单一根管治疗;观察组男31例、女20例,年龄(40.82±1.92)岁,病程(1.84±0.88)年,接受经皮穴位电刺激联合根管治疗。对比两组临床疗效、相关牙周指数[根尖周指数(PAI)、牙周探诊深度(PPD)、临床附着水平(CAL)]及炎性因子[肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、白细胞介素-8(IL-8)]水平。统计学方法采用t检验、χ^(2)检验。结果观察组治疗总有效率为94.12%(48/51),高于对照组的80.39%(41/51),差异有统计学意义(χ^(2)=4.320,P<0.05)。入组当天,两组患者PAI、PPD、CAL及TNF-α、IL-6、IL-8水平比较,差异均无统计学意义(均P>0.05);治疗1个月,观察组PAI、PPD、CAL及TNF-α、IL-6、IL-8水平均低于对照组[(1.28±0.45)分比(2.90±1.23)分、(1.14±0.35)mm比(3.20±1.36)mm、(1.12±0.33)mm比(2.16±0.47)mm、(11.88±1.81)ng/L比(28.55±3.95)ng/L、(89.29±5.80)ng/L比(191.02±9.58)ng/L、(41.76±9.40)ng/L比(98.47±8.85)ng/L],差异均有统计学意义(t=8.833、10.476、12.933、27.399、64.872、31.369,均P<0.05)。结论经皮穴位电刺激联合根管治疗可提升急性牙髓炎患者临床治疗效果,改善PAI、PPD、CAL水平,降低炎性因子分泌,对改善患者个体预后具有一定的临床应用价值。
Objective To investigate the clinical effect of percutaneous acupoint electrical stimulation combined with root canal therapy for patients with acute pulpitis.Methods This was a prospective study.One hundred and two patients with acute pulpitis admitted to Xi'an Third Hospital from April 2023 to April 2024 were selected as the study objects,and were randomly divided into a control group and an observation group,with 51 cases in each group.There were 29 men and 22 women in the control group;they were(40.57±2.16)years old;their disease course was(1.59±0.50)years.There were 31 men and 20 women in the observation group;they were(40.82±1.92)years old;their disease course was(1.84±0.88)years.The control group took root canal therapy,and the observation group took percutaneous acupoint electrical stimulation and root canal therapy.The clinical efficacies,periapical indexes(PAI),probing pocket depths,(PPD),clinical attachment levels(CAL),and levels of inflammatory factors[tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),and interleukin-8(IL-8)]were compared between the two groups.t and χ^(2) tests were applied.Results The total effective rate in the observation group was higher than that in the control group[94.12%(48/51)vs.80.39%(41/51)],with a statistical difference(χ^(2)=4.320;P<0.05).On the day of enrollment,there were no statistical differences in the PAI,PPD,CAL,and levels of TNF-α,IL-6,and IL-8 between the two groups(all P>0.05).At 1 month of treatment,the PAI,PPD,CAL,and levels of TNF-α,IL-6,and IL-8 in the observation group were lower than those in the control group[1.28±0.45 vs.2.90±1.23,(1.14±0.35)mm vs.(3.20±1.36)mm,(1.12±0.33)mm vs.(2.16±0.47)mm,(11.88±1.81)ng/L vs.(28.55±3.95)ng/L,(89.29±5.80)ng/L vs.(191.02±9.58)ng/L,and(41.76±9.40)ng/L vs.(98.47±8.85)ng/L],with statistical differences(t=8.833,10.476,12.933,27.399,64.872,and 31.369;all P<0.05).Conclusion Percutaneous acupoint electrical stimulation combined with root canal therapy for patients with acute pulpitis is effective and can improve their PAI,PPD,CAL,and prognosis and reduce the secretion of inflammatory factors.
作者
金英哲
伊远平
董瑜
冯蕾
Jin Yingzhe;Yi Yuanping;Dong Yu;Feng Lei(Department of Stomatology,Xi'an Third Hospital,Xi'an 710003,China)
出处
《国际医药卫生导报》
2024年第23期3895-3899,共5页
International Medicine and Health Guidance News
基金
陕西省重点研发计划(2024SF-YBXM-261)。
关键词
急性牙髓炎
经皮穴位电刺激
根管治疗
预后
Acute pulpitis
Electrical stimulation of percutaneous acupuncture points
Root canal therapy
Prognosis
