摘要
目的探讨老年患者无痛胃肠镜中应用多巴胺对术中循环以及术后认知功能的影响。方法选取2022年1月至2022年6月接受无痛胃肠镜检查的老年患者60例,随机分为对照组和观察组,每组各30例,观察组在诱导时予以多巴胺2 mg(1 mg/mL),对照组予以同剂量0.9%氯化钠,比较两组患者麻醉中循环以及术后认知评分的变化。结果两组无痛胃肠镜术后30 min内认知评分、短期POCD发生率以及诱导后循环比较,差异有统计学意义(P<0.05);多巴胺组与对照组相比更稳定(P<0.05)。结论在老年患者无痛胃肠镜中采用多巴胺进行静脉麻醉,有效减少血流动力学波动和降低术后认知障碍的发生,改善短期认知功能的变化。
Object To elucidate the effect caused by dopamine administrated during anesthesia induction for gastrointestinal endoscopy on intraoperative circulation and postoperative cognitive function in elderly patients.Methods Total 60 cases of elderly patients who underwent painless gastroenteroscopy from January 2022 to June 2022 were selected and randomly divided into the control group and the observation group,30 cases in each group,the observation group was given dopamine 2 mg(1 mg/mL)at the time of induction,and the control group was given the same dose of saline,and the changes in circulation during anaesthesia as well as in postoperative cognitive scores were compared between the two groups.Results Cognitive scores,incidence of short-term postoperative cognitive dysfunction(POCD)within 30 min after painless gastroenteroscopy,and post-induction circulation were compared between the two groups,and the differences were statistically significant(P<0.05);the dobutamine group was more stable compared with the control group(P<0.05).Conclusion The application of dopamine in the anesthesia for painless gastrointestinal endoscopy can mitigate hemodynamic fluctuation and POCD.
出处
《浙江临床医学》
2024年第11期1697-1699,共3页
Zhejiang Clinical Medical Journal
基金
浙江省海宁市科技计划社发项目(2021046)。
关键词
老年患者
麻醉
胃肠镜
多巴胺
术后认知并发症
Aged
Anesthesia
Gastroenteroscopy
Dopamine
Postoperative cognitive complications