摘要
目的:分析雷贝拉唑联合莫沙必利治疗功能性消化不良(FD)的效果。方法:选取2023年1月—2024年1月盐城市阜宁县中医院收治的80例FD患者进行研究,随机分为对照组(40例,给予枸橼酸莫沙必利治疗)和观察组(40例,给予雷贝拉唑联合莫沙必利治疗)。比较两组症状评分、临床疗效、胃肠排空率及不良反应发生情况。结果:治疗后,两组嗳气、上腹部疼痛、胃部烧灼感评分低于治疗前,且观察组低于对照组(P<0.05);观察组治疗总有效率高于对照组(P=0.006);治疗后,两组胃排空率、肠排空率高于治疗前,且观察组高于对照组(P<0.05)。两组不良反应总发生率无统计学差异(P>0.05)。结论雷贝拉唑联合莫沙必利治疗FD的效果显著,可促进患者症状改善和胃肠排空,且安全性较高。
Objective:To analyze the effect of rabeprazole combined with mosapride in treatment of functional dyspepsia(FD).Methods:A total of 80 FD patients admitted to Funing County Hospital of Traditional Chinese Medicine in Yancheng City from January 2023 to January 2024 were selected as the study subjects.They were randomly divided into the control group(40 cases,treated with mosapride citrate)and the observation group(40 cases,treated with rabeprazole combined with mosapride).The symptom scores,clinical efficacy,gastric emptying rate and adverse reactions were compared between the two groups.Results:After treatment,the scores of belching,epigastric pain and gastric burning sensation in the two groups were lower than those before treatment,and the scores in the observation group were lower than those in the control group(P<0.05).The total effective rate of treatment in the observation group was higher than that in the control group(P=0.006).After treatment,the gastric emptying rate and intestinal emptying rate in the two groups were higher than those before treatment,and these indexes in the observation group were higher than those in the control group(P<0.05).There was no statistically significant difference in the overall incidence of adverse reactions between the two groups(P>0.05).Conclusion:Rabeprazole combined with mosapride has a significant effect in the treatment of FD,and can improve the symptoms of patients,promote gastrointestinal emptying,and have a high safety.
作者
韦文锋
Wei Wenfeng(Emergency Department,Funing County Hospital of Traditional Chinese Medicine,Yancheng 224400,Jiangsu Province,China)
出处
《中国社区医师》
2024年第35期71-73,共3页
Chinese Community Doctors
