摘要
目的:观察中医综合诊疗方案在围术期不同分期的粉刺性乳痈患者的临床疗效。方法:采用前瞻性队列研究,连续纳入2021年4月—2022年12月在上海中医药大学附属曙光医院乳腺科住院治疗的围术期粉刺性乳痈患者200例,根据临床表现、辅助检查等将患者分为肿块期组75例、脓肿期组109例、瘘管期组16例。所有患者根据不同临床症状选用中药辨证论治、抗微生物药物、类固醇激素等内治法及箍围法、手术等外治法联合使用的治疗方案。评价中医综合诊疗方案治疗不同分期的粉刺性乳痈患者的切口愈合时间、痊愈时间、治愈率、复发率等。结果:在手术治疗后1个月和6个月,3组患者治愈情况无明显差异(P>0.05),中医综合诊疗方案治疗围术期粉刺性乳痈患者的治愈率分别为91.0%(182/200)、96.5%(193/200)。3组患者的切口痊愈时间比较,差异无统计学意义(P>0.05);3组患者的治疗至痊愈的时间比较,瘘管期组较脓肿期组更短(P<0.05);3组患者发病至痊愈的时间比较,肿块期组和脓肿期组均较瘘管期短(P<0.05),肿块期组与脓肿期组无明显差异(P>0.05)。3个不同分期的粉刺性乳痈患者的同侧复发、同侧新发、对侧新发例数分布无明显差异(P>0.05),中医综合诊疗方案治疗围术期粉刺性乳痈患者同侧复发率为5.5%,同侧新发率为1.5%,对侧新发率为1.5%。所有患者治疗期间均未出现过敏、神经兴奋、月经紊乱等不良反应,未出现肝肾功能异常。结论:中医综合诊疗方案对围术期粉刺性乳痈患者的治愈率高,总复发率低,疗效显著且安全性良好。
Objective:To observe the clinical efficacy of a comprehensive traditional Chinese medicine(TCM)treatment plan in perioperative patients with acne vulgaris of the breast at different stages.Methods:A prospective cohort study was conducted,enrolling 200 perioperative patients with acne vulgaris of the breast who were admitted to the Breast Department of Shuguang Hospital from April 2021 to December 2022.Patients were divided into three groups based on clinical presentation and auxiliary examinations:the mass stage group(75 cases),the abscess stage group(109 cases),and the fistula stage group(16 cases).All patients received a treatment plan combining internal treatments such as syndrome differentiation-based TCM,antimicrobial drugs,and corticosteroids,along with external treatments like compression therapy and surgery.The treatment efficacy was evaluated by measuring incision healing time,recovery time,cure rate,and recurrence rate.Results:One month and six months post-surgery,there was no significant difference in the cure rate among the three groups(P>0.05),with overall cure rates of 91.0%and 96.5%respectively.There was no significant difference in incision healing time among the three groups(P>0.05).However,the time to recovery was shorter in the fistula stage group compared to the abscess stage group(P<0.05).The total time from onset to recovery was shorter in the mass stage and abscess stage groups compared to the fistula stage group(P<0.05),with no significant difference between the mass stage and abscess stage groups(P>0.05).There was no significant difference in the distribution of same-side recurrence,new same-side occurrence,or new opposite-side occurrence among the three groups(P>0.05),with recurrence rates of 5.5%for same-side recurrence,1.5%for new same-side occurrence,and 1.5%for new opposite-side occurrence.No adverse reactions such as allergies,nervous excitability,menstrual disorders,or abnormal liver and kidney function were observed during the treatment.Conclusion:The comprehensive TCM treatment plan is highly effective and safe for perioperative patients with acne vulgaris of the breast,exhibiting a high cure rate and low recurrence rate.
作者
孙佳晔
万华
吴雪卿
高晴倩
瞿文超
邵士珺
谢璐
冯佳梅
SUN Jiaye;WAN Hua;WU Xueqing;GAO Qingqian;QU Wenchao;SHAO Shijun;XIE Lu;FENG Jiamei(Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200021,China)
出处
《中医药学报》
CAS
2025年第1期71-76,共6页
Acta Chinese Medicine and Pharmacology
基金
上海市卫生健康委员会科研课题(202040254)
上海中医药大学附属曙光医院国家自然科学基金青年孵育项目(SGKJLC-202016)。
关键词
中医综合诊疗方案
围术期
不同分期
粉刺性乳痈
临床应用
Comprehensive TCM treatment plan
Perioperative period
Different stages
Acne vulgaris of the breast
Clinical application
