摘要
目的:探讨多模态超声检查预测甲状腺乳头状癌(papillary carcinoma of the thyroid,PTC)患者发生颈部中央区淋巴结转移的价值。方法:选取2022年3月—2024年2月佛山市第一人民医院经术后病理学检查证实的PTC患者,术前均进行常规超声、剪切波弹性成像(shear wave elastography,SWE)及超微血管成像(superb microvascular imaging,SMI)检查。常规超声评估甲状腺病灶大小、位置、形态、内部实质回声、微钙化、纵横比以及甲状腺被膜连续性,SWE模式下测量甲状腺病灶杨氏模量平均值(Emean),SMI模式下测量病灶血管指数(vascular index,VI),采用单因素和多因素logistic回归分析PTC发生颈部中央区淋巴结转移的危险因素。结果:纳入的110例PTC患者术后病理学检查确诊伴中央区淋巴结转移52例(转移组),不伴中央区淋巴结转移58例(非转移组),两组患者年龄、甲状腺病灶最大径、形态、内部实质回声、微钙化、被膜连续性、Emean及VI值比较,差异有统计学意义(均P<0.05),多因素logistic回归分析结果显示患者年龄、病灶最大径、实质回声不均匀及Emean是PTC发生颈部中央区淋巴结转移的独立危险因素(均P<0.05)。结论:多模态超声检查对PTC预测颈部中央区淋巴结转移具有一定的临床价值。
Objective:To explore the value of multimodal ultrasound imaging in predicting central lymph node metastasis of papillary carcinoma of the thyroid(PTC).Methods:Patients with PTC confirmed by operation and pathology were selected in The First People’s Hospital of Foshan from March 2022 to February 2024.The patients were examined by conventional ultrasound,shear wave elastography(SWE)and superb microvascular imaging(SMI)before surgery.Conventional ultrasound was used to evaluate lesion maximum diameter,location,shape,internal parenchymal echo,microcalcification,the ratio of longitudinal and transverse diameter,capsule continuity.SWE was used to measure the mean of Young’s modulus(Emean).SMI was used to measure vascular index(VI).Single-factor and multi-factor logistic regression analysis were used to analyze the risk factors of the central lymph node metastasis in PTC patients.Results:A total of 110 patients included 52 patients with central lymph node metastasis(metastatic group)and 58 patients without central lymph node metastasis(non-metastatic group).There were significant differences in age,maximum diameter,shape,parenchymal echo,microcalcification,capsule continuity,Emean and VI between the two groups(all P<0.05).Multi-factor logistic regression analysis showed that age,maximum diameter,parenchymal echo and Emean were the independent risk factors of central lymph node metastasis(all P<0.05).Conclusion:Multimodal ultrasound has a certain value in predicting the central lymph node metastasis of PTC.
作者
何惠珍
叶洁仪
黄伟俊
HE Huizhen;YE Jieyi;HUANG Weijun(Department of Ultrasound Diagnosis and Treatment,The First People’s Hospital of Foshan,Foshan 528000,Guangdong Province,China)
出处
《肿瘤影像学》
2024年第6期609-614,共6页
Oncoradiology
基金
佛山市卫生健康局医学科研项目(20230038)。
关键词
甲状腺乳头状癌
多模态超声
剪切波弹性成像
超微血管成像
中央区淋巴结转移
Papillary carcinoma of the thyroid
Multimodal ultrasound
Shear wave elastography
Superb microvascular imaging
Central lymph node metastasis
