摘要
目的探讨精索静脉曲张(VC)超声分度在睾丸功能评估中的应用价值。方法选取2021年7月至2022年12月于四川省人民医院就诊的152例VC患者为研究对象,根据VC严重程度将其分为轻度组(n=47)、中度组(n=51)和重度组(n=54)。通过超声测量3组精索静脉内径、反流时间及睾丸尺寸,计算睾丸容积和萎缩指数(AI),比较3组年龄、体重指数(BMI)、吸烟史、饮酒史、睾丸尺寸、精液、睾酮及血清卵泡刺激素(FSH),采用多个独立样本秩和检验、多因素Logistic回归分析不同VC超声分度与睾丸功能的相关性。结果3组年龄、BMI比较,差异有统计学意义(P<0.05)。3组睾丸AI、精子浓度、精子活力、血清FSH、睾酮比较,差异有统计学意义(P<0.05)。随着VC程度加重,3组睾丸AI和血清FSH的异常率均呈升高趋势。控制BMI、吸烟、饮酒和年龄等因素后,轻度组患病风险较重度组低,差异有统计学意义(P<0.05),重度组患病风险与中度组比较,差异无统计学意义(P>0.05)。结论VC超声分度与睾丸功能变化密切相关,超声分度可作为睾丸功能的评估指标。
Objective To explore the application value of ultrasound grading of varicocele(VC)in the assessment of testicular function.Methods A total of 152 patients with VC in Sichuan Provincial People's Hospital from July 2021 to December 2022 were selected as the research objects.The patients were divided into a mild group(n=47),a moderate group(n=51),and a severe group(n=54)according to the severity of their VC.The internal diameter of the spermatic vein,reflux time,and testicular dimensions in the three groups were measured by ultrasound.The testicular volume and atrophy index(AI)were calculated.The age,body mass index(BMI),smoking history,drinking history,testicular dimensions,semen examination,testosterone,and serum follicle-stimulating hormone(FSH)of the three groups were statistically analyzed.And the correlation between different VC ultrasound grades and changes in testicular function was analyzed using multiple independent samples rank test and multivariate Logistic regression.Results Comparison of age and BMI among the 3 groups showed statistically significant differences(P<0.05).Testicular AI,sperm concentration,sperm viability,serum FSH,and testosterone among the 3 groups showed statistically significant differences(P<0.05).With the aggravation of the degree of VC,the abnormal rate of testicular AI and serum FSH tended to increase in all 3 groups.After controlling for BMI,smoking,alcohol consumption and age,the risk of disease in the mild group was lower than that in the severe group,and the difference was statistically significant(P<0.05),while the risk of disease in the severe group was not statistically significant compared with that in the moderate group(P>0.05).Conclusion VC ultrasound grading is greatly correlated with changes in testicular function.Ultrasound grading is one of the reliable indicators for assessing testicular function.
作者
王璨
刘健
冯强
万永强
谭春英
Wang Can;Liu Jian;Feng Qiang;Wan Yongqiang;Tan Chunying(Department of Medical Ultrasound,Sichuan Academy of Medical Sciences·Sichuan Provincial People's Hospital,Chengdu 610072,China;Department of Ultrasound,The First Affiliated Hospital of Chengdu Medical College,Chengdu 610500,China;Department of Urology,Sichuan Academy of Medical Sciences·Sichuan Provincial People's Hospital,Chengdu 610072,China)
出处
《成都医学院学报》
2025年第1期119-122,共4页
Journal of Chengdu Medical College
关键词
精索静脉曲张
超声分度
精液分析
睾丸功能
Varicocele
Ultrasound grading
Semen analysis
Testicular function
