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肺部超声指导新生儿呼吸窘迫综合征和短暂性呼吸增快继发肺实变患儿治疗的临床价值

Clinical value of lung ultrasound in guiding the treatment of secondary pulmonary consolidation in children caused by neonatal respiratory distress syndrome and transient tachypnea of the newborn
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摘要 目的探讨肺部超声(LUS)在指导新生儿呼吸窘迫综合征(NRDS)和短暂性呼吸增快(TTN)继发肺实变患儿使用肺表面活性物质(PS)治疗中的临床价值。方法选取我院收治的胎龄<34周早产儿217例,均于出生后进行LUS检查,若LUS提示肺实变则给予PS治疗;PS治疗后复查LUS监测肺复张情况决定是否再次使用PS治疗,分析患儿治疗效果。结果纳入的217例早产儿经临床及LUS检查诊断为NRDS 55例(25.35%),TTN 37例(17.05%)。55例NRDS患儿中,第1次使用PS治疗后LUS提示33例完全肺复张,第2次使用PS治疗后LUS提示14例完全肺复张,第3次使用PS治疗后LUS提示6例完全肺复张。37例TTN患儿中继发肺实变6例(16.22%),第1次使用PS治疗后LUS提示4例完全肺复张,第2次使用PS治疗后LUS提示2例完全肺复张。结论根据LUS提示是否存在肺实变能精准指导NRDS和TTN继发肺实变患儿使用PS治疗并评估其疗效,有一定的临床价值。 Objective To explore the clinical value of lung ultrasound(LUS)in guiding the treatment of pulmonarysurfactant(PS)in children with secondary pulmonary consolidation caused by neonatal respiratory distress syndrome(NRDS)and transient tachypnea of the newborn(TTN).Methods A total of 217 preterm infants with gestational age<34 weeks were selected for LUS examination after birth.When LUS imaging indicated lung consolidation,PS treatment was given.After PS treatment,LUS was used to monitor pulmonary reexpansion and determine whether to use PS again,and the treatment effect of the children was analyzed.Results Among the 217 preterm infants,55 cases(25.35%)of NRDS and 37 cases(17.05%)TTN were diagnosed by clinic combined with LUS examination.Among the 55 children with NRDS,33 cases were completely reexpand by LUS after the first PS treatment,14 cases were completely reexpand after the second PS treatment,and 6 cases were completely reexpand after the third PS treatment.Among 37 children with TTN,6 cases(16.22%)had secondary lung consolidation.In these 6 children,after the first PS treatment,the LUS showed complete lung reexpansion in 4 cases,and after the second PS treatment,the LUS showed complete lung reexpansion in 2 cases.Conclusion According to the presence or absence of lung consolidation by LUS imaging can accurately guide the PS treatment of children with secondary pulmonary consolidation caused by NRDS and TTN,and evaluate its efficacy,which has a certain clinical value.
作者 封在李 黄娜 周理存 徐芳 雷嘉 吴凡 杨明杰 李蕊 郭云华 FENG Zaili;HUANG Na;ZHOU Licun;XU Fang;LEI Jia;WU Fan;YANG Mingjie;LI Rui;GUO Yunhua(Department of Neonatology,Dehong Hospital Affiliated to Kunming Medical University,Mangshi 678400,China;Department of Science and Education,Dehong Hospital Affiliated to Kunming Medical University,Mangshi 678400,China;Kunming Medical University,Kunming 650000,China;Dehong Vocational College,Mangshi 678400,China;Department of Emergency Medicine,Dehong Hospital Affiliated to Kunming Medical University,Mangshi 678400,China;Department of Obstetrics,Dehong Hospital Affiliated to Kunming Medical University,Mangshi 678400,China;Department of Ultrasound,Dehong Hospital Affiliated to Kunming Medical University,Mangshi 678400,China)
出处 《临床超声医学杂志》 2025年第1期23-26,共4页 Journal of Clinical Ultrasound in Medicine
基金 云南省科技厅科技计划项目(202201AY070001-220) 云南省教育厅科学研究基金项目(2019J1316) 德宏州中青年学术和技术带头人后备人才(英才兴边)计划(2023RC001) 德宏州科技计划项目(zc202411,zc202410) 德宏州人民医院科学研究基金项目(2022DY008)。
关键词 超声检查 呼吸窘迫综合征 短暂性呼吸增快 新生儿 肺实变 肺表面活性物质 Ultrasonography,lung Respiratory distress syndrome Transient tachypnea Neonatal Lung consolidation Pulmonarysurfactant

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