摘要
目的:观察艾灸干预对卒中后认知障碍(PSCI)患者认知功能和执行功能的临床疗效及对血清同型半胱氨酸(Hcy)的调控作用。方法:招募2023年5月—2023年11月入住福建省康复医院的104例PSCI患者,随机分为艾灸组和对照组,每组52例。对照组接受康复训练与常规护理;艾灸组在对照组治疗基础上进行艾条悬起灸。两组均干预4周。比较两组患者认知功能(MoCA-ChiFZ)、执行功能(VFT、SCWT、TMT)、血清同型半胱氨酸(Hcy)及日常生活活动能力评分(MBI)。结果:对照组和艾灸组患者分别有48例和47例最终完成试验。对照组治疗后的MoCA-ChiFZ总分及视空间与执行能力、注意、延迟回忆3个分维度的得分较治疗前明显提高,差异具有统计学意义(P<0.05);艾灸组治疗后MoCAChiFZ总分及7个分维度评分均较治疗前增高明显,差异具有统计学意义(P<0.05);艾灸组患者MoCA-ChiFZ评分较对照组提高明显,差异具有统计学意义(P<0.05)。与治疗前比较,两组患者VFT提高、SCWT评分中耗时减少而正确数增加、TMT评分耗时减少而TMT-B错误数减少,差异具有统计学意义(P<0.05)。治疗后,两组患者MBI评分较治疗前升高明显,血清Hcy水平较治疗前降低,差异有统计学意义(P<0.05)。治疗后,艾灸组患者MBI评分较对照组提高,SCWT的卡片B和C的耗时及TMT的A和B耗时均较对照组明显减少,SCWT的卡片C和SCWT中反应干扰量的正确数明显增多,差异均具有统计学意义(P<0.05)。结论:通过艾灸治疗可有效提升PSCI患者的认知功能、执行功能,改善患者的ADL。
Objective:To observe the clinical effect of moxibustion intervention on cognitive function and executive function in patients with post-stroke cognitive impairment(PSCI)and its regulatory effect on serum homocysteine(Hcy).Methods:A total of 104 patients with PSCI who were admitted to Fujian Rehabilitation Hospital from May 2023 to November 2023 were selected and randomly divided into the moxibustion group and the control group,with 52 cases in each group.Patients in the control group received rehabilitation training and routine nursing.Patients in the moxibustion group were treated with suspended moxa stick moxibustion on the treatment basis of the control group.Intervention duration in both groups was 4 weeks.Cognitive function(MoCA-ChiFZ),executive function(VFT,SCWT and TMT),Hcy and activity of daily living(MBI)scores were compared between the two groups.Results:A total of 48 patients in the control group and 47 patients in the moxibustion group finally completed the trial.In the control group,the total score of MoCA-ChiFZ and the scores of three sub-dimensions of visual space and executive ability,attention and delayed recall after treatment were significantly higher than those before treatment,and the differences were statistically significant(P<0.05).The total Mo-CAChiFZ score and 7 sub-dimension scores of the moxibustion group after treatment were significantly higher than those before treatment,and the differences were statistically significant(P<0.05).The MoCA-ChiFZ score of the moxibustion group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).Compared with before treatment,the VFT was increased,the time spent in SCWT was reduced and the number of correct was increased,the time spent in TMT score was reduced and the number of errors was reduced in the two groups,and the differences were statistically significant(P<0.05).After treatment,the MBI scores of the two groups were significantly higher than those before treatment,and the serum Hcy levels were lower than those before treatment,with the statistical significance(P<0.05).After treatment,the MBI score of the moxibustion group was higher than that of the control group,the time-consuming of card B and C of SCWT and the time-consuming of A and B of TMT were significantly lower than those of the control group, and the correct number of reaction interference in card C of SCWT and SCWT were significantly increased,with the statistical significance (P<0.05). Conclusion: Moxibustion treatment can effectively improve the cognitivefunction, executive function and ADL of patients with PSCI.
作者
刘芳
修火琴
林茜
苏桂婷
邱莉
高姗
Liu Fang;Xiu Huoqin;Lin Qian;Su Guiting;Qiu Li;Gao Shan(School of Nursing,Fujian University of Traditional Chinese Medicine,Fuzhou Fujian 350122;Department of Speech Therapy,Rehabilitation Hospital Affiliated to Fujian University of Traditional Chinese Medicine,Fuzhou Fujian 350003;Fujian Key Laboratory of Rehabilitation Technology,Fuzhou Fujian 350003)
出处
《山西中医药大学学报》
2025年第1期85-91,共7页
Journal of Shanxi University of Chinese Medicine
基金
福建省自然科学基金项目(2021J01946)
福建中医药大学护理学科开放课题(XHL2022005)。
