摘要
目的分析乳腺癌患者首次行紫杉类药物化疗期间情绪障碍发生情况,观察个性需求调查后实施针对性干预的临床效果。方法以2016年6月至2022年6月中国人民解放军联勤保障部队第九八〇医院收治的120例首次行紫杉类药物化疗的乳腺癌患者为研究对象,采用改良焦虑自评量表(SAS)和改良抑郁自评量表(SDS)评价患者是否存在情绪障碍及具体程度,然后筛选出有情绪障碍的患者,根据抽签法随机分为观察组和对照组,分别进行个性需求调查,对照组进行常规治疗及干预,观察组在对照组基础上依据患者的个性需求调查问卷结果给予针对性干预措施。比较观察组和对照组患者干预前后个性需求调查问卷评分、SAS评分、SDS评分及简式简明心境问卷(POMS-SF)评分变化,以及2组化疗期间恶心呕吐情况。结果120例乳腺癌患者中95例患者有情绪障碍,占79.17%。干预后,观察组和对照组患者乳腺癌医学知识需求、身体健康教育内容、心理健康获得观念评分均较本组干预前升高(P<0.05),且观察组各项评分均高于对照组(P<0.05)。干预后,2组患者SAS、SDS评分均较本组干预前降低(P<0.05),且观察组SAS、SDS评分均低于对照组(P<0.05)。干预后,2组POMS-SF中紧张-焦虑、抑郁-沮丧、愤怒-敌意、疲乏-迟钝、迷惑-混乱评分均下降(P<0.05),精力-活力评分均升高(P<0.05),且观察组紧张-焦虑、抑郁-沮丧、迷惑-混乱评分低于对照组(P<0.05),精力-活力评分高于对照组(P<0.05)。化疗期间观察组恶心呕吐程度分级低于对照组(P<0.05)。结论乳腺癌患者首次行紫杉类药物化疗期间情绪障碍发生率较高,针对个性需求调查结果实施针对性的干预措施能够改善患者的情绪障碍。
Objective To analyze the incidence of emotional disorders in patients with breast cancer during their first taxane chemotherapy and observe the clinical efficacy of targeted interventions after an investigation of individual needs.Methods A total of 120 breast cancer patients who received their first taxane chemotherapy at the 980 Hospital of the People's Liberation Army Joint Logistics Support Forces from June 2016 to June 2022 were selected as the research subjects.The Modified Self-Rating Anxiety Scale(SAS)and the Modified Self-Rating Depression Scale(SDS)were used to evaluate whether the patients had emotional disorders and the specific degree.Then,the patients with emotional disorders were screened out and randomly divided into an observation group and a control group by the lottery method.Individual needs surveys were conducted for both groups.The control group received conventional treatment and interventions,while the observation group was given targeted intervention measures based on the results of the individual needs questionnaires on top of the control group's treatment.The changes in the scores of the individual needs questionnaires,SAS scores,SDS scores,and Profile of Mood StatesShort Form(POMS-SF)scores before and after the intervention were compared between the observation group and the control group,as well as the nausea and vomiting conditions during chemotherapy in the two groups.Results Among the 120 breast cancer patients,95 had emotional disorders,accounting for 79.17%.After the intervention,the scores of breast cancer medical knowledge needs,physical health education content,and mental health acquisition concepts in both the observation group and the control group were higher than those before the intervention in their respective groups(P<0.05),and all the scores in the observation group were higher than those in the control group(P<0.05).After the intervention,the SAS and SDS scores of both groups were lower than those before the treatment in their respective groups(P<0.05),and the SAS and SDS scores of the observation group were lower than those of the control group(P<0.05).After the intervention,the scores of tension-anxiety,depression-dejection,anger-hostility,fatigue-dullness,and confusion-chaos in the POMS-SF of both groups decreased(P<0.05),and the score of vigor-vitality increased(P<0.05),and the scores of tension-anxiety,depression-dejection,and confusion-chaos in the observation group were lower than those in the control group(P<0.05),and the score of vigor-vitality was higher than that in the control group(P<0.05).During chemotherapy,the nausea and vomiting degree classification of the observation group was lower than that of the control group(P<0.05).Conclusion The incidence of emotional disorders is high in patients with breast cancer during their first taxane chemotherapy.Implementing targeted intervention measures based on the results of individual needs surveys can improve the emotional disorders of patients.
作者
侯春立
景凤敏
陈连刚
张翠红
HOU Chunli;JING Fengmin;CHEN Liangang;ZHANG Cuihong(Department of Medical Oncology,980 Hospital of the People's Liberation Army Joint Logistics Support Forces,Shijiazhuang,Hebei 050082,China;Department of Radiation Oncology,980 Hospital of the People's Liberation Army Joint Logistics Support Forces,Shijiazhuang,Hebei 050082,China;Department of Medical Records Management,The Second Hospital of Hebei Medical University,Shijiazhuang,Hebei 050000,China)
出处
《转化医学杂志》
2024年第10期1689-1693,共5页
Translational Medicine Journal
基金
2016年度河北省医学科学研究重点课题计划(20160003)。
关键词
乳腺肿瘤
化疗
情绪障碍
个性需求
针对性干预
Breast neoplasm
Chemotherapy
Emotional fisorders
Individual needs
Targeted intervention
