摘要
目的:对老年2型糖尿病(T2DM)合并肌少症患者的营养状态进行调查,并分析影响患者肌少症发生的危险因素,为临床防治提供依据。方法:选取2021年2月—2024年6月在我院就诊的老年T2DM患者380例,根据是否合并肌少症将其分为肌少症组168例和非肌少症组212例。分析和比较两组患者的营养状态,并分析影响老年T2DM患者合并肌少症的危险因素。结果:肌少症组体质量指数(BMI)、上臂肌围、血红蛋白、白蛋白以及微型营养评估量表(MNA)评分均明显低于非肌少症组(t值分别为-30.419、-10.397、-14.053、-10.915、-22.688,P<0.05);肌少症组与非肌少症组在年龄、合并慢性疾病种类、空腹血糖(FPG)、糖化血红蛋白(HbA1c)、每日运动时间、营养不良发生比例等资料方面比较差异具有统计学意义(χ^(2)/t值分别为15.831、5.855、 6.579、8.181、 44.936、 24.384, P<0.05);多因素Logistic回归分析显示,低BMI(OR=0.567, 95%CI:0.385~0.834)、上臂肌围下降(OR=0.762,95%CI:0.644~0.906)、血红蛋白下降(OR=0.693,95%CI:0.474~0.993)、白蛋白降低(OR=0.680, 95%CI:0.482~0.961)、 MNA评分降低(OR=0.470, 95%CI:0.285~0.774)、高龄(OR=4.622,95%CI:2.119~10.083)、FPG升高(OR=2.643,95%CI:1.387~5.036)、HbA1c升高(OR=3.943,95%CI:1.626~9.561)、每日运动时间<30min(OR=5.359,95%CI:2.330~12.236)、营养不良(OR=5.078,95%CI:1.822~14.151)属于影响老年T2DM合并肌少症的独立危险因素。结论:老年T2DM合并肌少症患者的营养状态较差,其中低BMI、上臂肌围下降、血红蛋白下降、白蛋白降低、MNA评分降低、高龄、FPG升高、HbA1c升高、每日运动时间<30min、营养不良属于影响老年T2DM合并肌少症的独立危险因素。
【Objective】To investigate the nutritional status of elderly patients with type 2 diabetes mellitus(T2DM)complicated with sarcopenia,and analyze the risk factors of sarcopenia,so as to provide the basis for clinical prevention and treatment.【Method】A total of 380 elderly T2DM patients admitted to our hospital from February 2021 to June 2024 were selected and divided into a sarcopenia group(168 cases)and a non-sarcopenia group(212 cases)according to whether they were complicated with sarcopenia.The nutritional status of the two groups of patients was analyzed and compared,and the risk factors affecting the elderly patients with T2DM complicated with sarcopenia were analyzed.【Result】Body mass index(BMI),upper arm muscle circumference,hemoglobin,albumin and micronutrition assessment scale(MNA)scores in sarcopenia group were significantly lower than those in non-sarcopenia group(t-values were-30.419,-10.397,-14.053,-10.915,-22.688,P<0.05).There were statistically significant differences between the sarcopenia group and the non-sarcopenia group in terms of age,types of chronic diseases,fasting blood glucose(FPG),glycosylated hemoglobin(HbA1c),daily exercise time,and incidence of malnutrition(χ^(2)/t value was 15.831,5.855,6.579,6.579,respectively).8.181,44.936,24.384,(P<0.05);Multivariate Logistic regression analysis showed low BMI(OR=0.567,95%CI:0.385-0.834),lower upper arm muscle circumference(OR=0.762,95%CI:0.644-0.906),and lower hemoglobin(OR=0.693,95%CI:0.474-0.993),decreased albumin(OR=0.680,95%CI:0.482-0.961),decreased MNA score(OR=0.470,95%CI:0.285-0.774),advanced age(OR=4.622,95%CI:2.119-10.083),FPG increased(OR=2.643,95%CI:1.387-5.036),HbA1c increased(OR=3.943,95%CI:1.626-9.561),daily exercise time<30min(OR=5.359,95%CI:2.330-12.236)and malnutrition(OR=5.078,95%CI:1.822-14.151)were independent risk factors for elderly patients with T2DM complicated with sarcopenia.【Conclusion】The nutritional status of elderly T2DM patients with sarcopenia was poor,among which,low BMI,decreased upper arm muscle circumference,decreased hemoglobin,decreased albumin,decreased MNA score,advanced age,increased FPG,increased HbA1c,daily exercise time<30min and malnutrition were independent risk factors for elderly T2DM patients with sarcopenia.
作者
段丽春
张丽艳
刘小燕
雷丽
李又聪
艾双
DUAN Li-chun;ZHANG Li-yan;LIU Xiao-yan;Lei LI;LI You-cong;AI Shuang(Nutrition Department of the 964 Hospital of the PLA Joint Service Support Force,Changchun 130062,China;Disease Prevention and Control Department of the 964 Hospital of the PLA Joint Service Support Force,Changchun 130062,China;Disinfection Supply Room of the 964 Hospital of the PLA Joint Service Support Force,Changchun 130062,China;Outpatient Department of the 964 Hospital of the PLA Joint Service Support Force,Changchun 130062,China)
出处
《中国食物与营养》
2025年第2期96-100,共5页
Food and Nutrition in China
关键词
2型糖尿病
老年
肌少症
营养状况
影响因素
type 2 diabetes mellitus
old age
sarcopenia
nutritional status
influencing factor
