摘要
衰弱是一种多器官功能减退引起的机体易损性增加的临床状态,临床表现为行动迟缓、活动减少、能量水平降低和非自主的体重减轻。衰弱使老年人面对应激事件时发生失能、长期住院治疗及死亡的风险增加。早期评估衰弱并进行个性化干预,可以预防和延缓衰弱的进展,进而减少负性事件的发生。本文检索2015年1月—2024年1月国内外发表的衰弱研究相关文献,对老年人衰弱的评估工具,如临床衰弱量表、衰弱指数、Fried表型量表、FRAIL量表和生物标志物,以及衰弱的干预,如运动锻炼、营养干预、口腔管理和药物管理等进行综述,为早期评估和干预老年人衰弱提供依据。
Frailty is a clinical state characterized by increased vulnerability due to the decline of multiple organ functions.It is clinically manifested as slow movement,reduced activity,low energy level and involuntary weight loss.Frailty heightens the risk of disability,long-term hospitalization and mortality in the elderly when they face stressful events.Early assessment of frailty and personalized interventions can prevent and delay its progression,thereby reducing the occurrence of adverse events.This article reviews the literature on frailty published both domestically and internationally from January 2015 to January 2024.It provides an overview of the tools for assessing frailty in the elderly,such as the Clinical Frailty Scale,Frailty Index,Fried Frailty Phenotype,FRAIL Scale,and biological markers,and the management of frailty,including exercise,nutritional interventions,oral health management,and medication management,so as to provide the evidence for early assessment and intervention of frailty.
作者
郭亮梅(综述)
宋文娟(综述)
曾强(审校)
GUO Liangmei;SONG Wenjuan;ZENG Qiang(The Second Medical Center&National Clinical Research Center for Geriatric Diseases,Chinese PLA General Hospital,Beijing 100039,China)
出处
《预防医学》
2025年第3期262-266,共5页
China Preventive Medicine Journal
基金
国家老年疾病临床医学研究中心项目(NCRCG-PLAGH-2024002)。
关键词
老年人
衰弱
评估
干预
the elderly
frailty
assessment
intervention
