摘要
1 Introduction The process of complex diseases is closely linked to the disruption of key biological pathways,it is crucial to identify the dysfunctional pathways and quantify the degree of dysregulation at the individual sample level[1].
基金
supported in part by the National Natural Science Foundation of China(Grant No.62202383)
Guangdong Basic and Applied Basic Research Foundation(No.2024A1515012602)
the National Key Research and Development Program of China(No.2022YFD1801200).
