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改进的大鼠异位心脏移植术 被引量:9

Improved Heterotopic Heart Transplantation in Rats
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摘要 作者采用Ono创建的大鼠异位心脏移植模型,即将供体升主动脉和肺动脉分别与受体腹主动脉和下腔静脉吻合。对手术方法作了部分改进,手术时间和供心缺血时间缩矩,供心保护良好。52次正式实验手术成功率为88%,手术失败的主要原因是吻合口出血,减少术中出血是保证手术成功的关键,作者着重介绍了改进的大鼠异位心脏移植术的方法和经验。 The authors adopted the model of rat heart heterotopic transplantation established by Ono who anastomosed the donor ascending aorta and pulmonary artery to the recipient abdominal aorta and inferior vena cava respectively, and sonie improvemenLs on this model were made in this experimenL The time of procedure and the ischemic time of the donor heart were shortened, and the protection of the donor heart was satisfactory. The successful rate of 52 formal transplantations was 88%. The main reason of surgical failure is bleeding from the anastomosis. To lessen the intraoperative bleeding is a key factor to make the procedure successful. The method of the improved experimental model and the expenence are described in details.
机构地区 长海医院胸外科
出处 《第二军医大学学报》 CAS CSCD 北大核心 1992年第2期116-119,共4页 Academic Journal of Second Military Medical University
关键词 移植 心脏 大鼠 transplantalion homologous heart rats
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参考文献1

  • 1龙国粹,人造心脏瓣膜与瓣膜置换术,1986年

同被引文献36

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  • 2邹良建,张宝仁,朱家麟,郝家骅,蔡凯华.改良豚鼠至大鼠异种异位心脏移植模型[J].第二军医大学学报,1995,16(5):446-448. 被引量:3
  • 3陈凡.心脏移植排斥的效应机制[J].国外医学(免疫学分册),1996,19(4):197-200. 被引量:5
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