摘要
目的 调查解脲支原体 (UU)在正常人群中宫颈的存在情况及其分群分型。方法 用液体选择培养基初筛北大医院妇科体检人群 2 6 1例 ,提取DNA ,用PCR法进行分群分型。结果 初筛 2 6 1例中UU阳性 15 9例 ( 6 0 9% ) ,其中生物一群 (parvumbiovar) 15 1例 ( 95 0 % ) ,生物二群 (urealyticumbiovar) 8例 ( 5 0 % ) ;生物一群中血清 1型 30例 ( 19 9% ) ,血清 3型 6 2例 ( 41 1% ) ,血清 6型 44例 ( 2 9 1% ) ,血清 14型 2例 ( 1 3 % ) ,混合感染13例 ( 8 6 % )。结论 在正常人群中 ,UU感染仅与绝经与否有统计学差异 (P <0 0 5 ) ,与年龄、宫颈炎、细菌性阴道病、真菌以及滴虫感染均无统计学差异。UU在正常人群中的感染率很高 ( 6 0 9% ) ,主要以生物一群为主( 95 0 % ) ,而且感染以 1、3、6型单纯感染为主 ( 90 1% ) ,其 1、3、6各型的感染率基本相似 ( 19 9%、41 1%、2 9 1% )。所以正常人群中单纯从宫颈分离出UU并不意味着致病性。
ObjectiveTo investigate the existence of ureaplasma urealyticum (UU) in cervix in gynecologic check-up population and its biovars and serotypes. Methods261 gynecologic check-up cases were collected from gynecologic clinic of Beijing University First Hospital. Swabs taken from cervix were cultured by commercial UU selective liquid medium. The positive cases were then classified into biovars and serotypes by PCR method. Results261 cases were screened and 159 cases were found to be UU positive by culture (60.9%). In UU positive cases, 151 were parvum biovar (95.0%) and 8 were urealyticum biovar (5.0%). In parvum biovar, serotype 1, 3, 6 and 14 were in 30 cases (19.9%), 62 cases (41.1%), 44 cases (29.1%) and 2 cases (1.3%) respectively. The mixed infections of these four serotypes were in 13 cases (8.6%). ConclusionsIn normal population, the UU cervical infection only shows statistically significant difference between premenopausal and menopausal women (P0.016). UU cervical infections have no relationship with age, cervical erosion, cervicitis, bacterial vaginitis, fungus and trichomoniasis infections. The cervical infection of UU is relatively high in normal population, which means that simple finding of UU in cervix hasn't pathogenicity. The main infective biovar is parvum biovar and single infection caused by serotypes of parvum biovar is dominant in normal population.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2003年第3期161-163,共3页
Chinese Journal of Practical Gynecology and Obstetrics
