摘要
①目的 探讨红细胞膜唾液酸 (RBCm SA)含量及红细胞免疫功能 (RBCIF)与急性脑梗死 (ACI)的关系。②方法 检测了 19例ACI病人RBCm SA、血浆唾液酸 (P SA)、循环免疫复合物 (CIC)的含量及RBCIF ,并与2 8例正常人进行比较。③结果 ACI病人RBCm SA和RBCIF低于正常人 (t=- 2 .5 12 ,P <0 .0 5 ;t=- 3.12 1,P<0 .0 1) ,而P SA和CIC高于正常人 (t=2 .875 ,P <0 .0 1;t=2 .4 0 3,P <0 .0 5 )。不论正常人还是病人 ,RBCm SA与RBCIF呈正相关 (r =0 .4 97,P <0 .0 1;r =0 .4 83,P <0 .0 5 ) ,RBCm SA与P SA呈负相关 (r =- 0 .4 6 6、- 0 .5 0 6 ,P <0 .0 5 )。④结论 ACI病人红细胞免疫功能降低与RBCm SA代谢异常相关。
Objective To evaluate the relationship between acute cerebral infarction(ACI) and red blood cell membrane sialic acid(RBCm SA) as well as red blood cell immune functions(RBCIF). \ Methods\ RBCm SA, plasma sialic acid(P SA), RBCIF and circulating immune complexes(CIC)in 19 patients with ACI were detected, and compared with 28 normal controls. \ Results\ RBCm SA and RBCIF in the patients were significantly lower than those in the controls ( t=-2.512,P<0.05;t=-3.121,P <0.01), and P SA and CIC in the patients were significantly higher in comparison with the controls ( t=2.875,P<0.01;t= 2.403 ,P <0.05). Positive correlation was found between RBCm SA and RBCIF ( r=0.497,P<0.01;r=0.483,P <0.05), and negative one was showed between RBCm SA and P SA ( r=-0.466,-0.506,P <0.05). \ Conclusion\ The decrease of RBC immune function in patients with ACI is related to the metabolism disorder of RBCm SA.
出处
《青岛大学医学院学报》
CAS
2003年第1期56-57,共2页
Acta Academiae Medicinae Qingdao Universitatis
关键词
脑梗死
红细胞
唾液酸类
免疫测定
cerebral infarction
erythrocyte
sialic acids
immunoassy
