摘要
目的 :探讨虎参痛风丸的镇痛效果及急性毒性。方法 :分别观察虎参痛风丸高、中、低三个剂量组对小鼠冰醋酸所致的扭体反应、热板法致痛的影响。观察最大浓度药液对小鼠的急性毒性反应。结果 :虎参痛风丸能显著抑制小鼠冰醋酸所致的扭体反应、减轻热板刺激所致的疼痛 ;虎参痛风丸无明显急性毒性反应。结论
AIM: To evaluate the analges ic effects and acute toxicity of hushentongfengwan (Hus). METHODS: The analgesic effects were tested by writhing reaction and hot-plate method and acute toxicity was observed in mice. RESULTS: Hus could res train writhing reaction caused by acetic acid glacial, lighten the pain caused b y hot-plate, and it did not show any reactions of acute toxicity. CONC LUSION: Hus had significant analgesic action.
出处
《中国临床药理学与治疗学》
CAS
CSCD
2003年第3期323-325,共3页
Chinese Journal of Clinical Pharmacology and Therapeutics
