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油漆工淋巴细胞染色体畸变率和微核率的变化 被引量:4

The rate of chromosome aberration and lymphocyte micronucleus in painter
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摘要 目的 探讨居室装饰油漆工外周血淋巴细胞染色体畸变率和微核发生率的变化。方法 应用气相色谱法测定工作场所苯等有机溶剂浓度 ,按常规方法检测外周血淋巴细胞染色体畸变率和微核发生率。结果 在工作场所空气中苯等有机溶剂浓度超标 2~ 2 5倍 ,接触组工人外周血淋巴细胞微核发生率为 7 12‰ ,对照组为 1 5 6‰ ;染色体畸变率接触组为 2 62 % ,对照组为 0 62 % ,接触组均显著高于对照组 (P <0 0 1)。结论 油漆工作业场所苯等有机溶剂浓度严重超标 ,致使作业工人外周血淋巴细胞染色体畸变率和微核发生率升高。 Objective To study the possibility and degree of chromosome aberration and micronucleus rates of painting in indoor decoration. Methods 30 workers who had been working in indoor painting for long time were randomly selected from building labour market, half for men and half for women. Concentrations of benzene etc. in workplaces were measured. Chromosome aberration and micronucleus rates of lymphocyte in periphery blood were tested by regular method. Results Concentrations of benzene etc. in workplaces air were 2~25 times over hygienic standard. Micronucleus rates of lymphocyte in periphery blood were 7.12‰ in exposure groups and 1.56‰ in control; chromosome aberration rate were 2.62% in exposure groups and 0.62% in control. The two indices in exposure group were higher than those in control ( P <0.01). Conclusion Concentrations of benzene etc. in workplaces air seriously exceeded hygienic standard in indoor decoration. The increase of chromosome aberration and micronucleus rates of lymphocyte in periphery blood were observed.
出处 《中国职业医学》 CAS 北大核心 2003年第3期30-32,共3页 China Occupational Medicine
关键词 油漆工 染色体畸变率 微核发生率 Painter Chromosome aberration rate Micronucleus rate
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  • 1周建平 孙慰祖.健康影响若干问题探讨[A]..全国市内装饰卫生安全评价学术研讨会资料集[C].北京:中国毒理学会、健康报社、中国毒理学会工业毒理委员会,2001.6.22—26.
  • 2高星.急性涂料中毒及其预防对策.全国市内装饰卫生安全评价学术研讨会资料集[M].北京:中国毒理学会、健康报社、中国毒理学会工业毒理委员会,2001.6.1—9.
  • 3Zhang L, Rothman N, Wang Y, et al. Interphase cytogenetics of workers exposed to benzene[J]. Environ Health Perspect, 1996, 104:1325 -1329.
  • 4Song-Nian Yin, Richard BH, Martha SL, et al, A cohort study of cancer among benzene exposed workers in China overall results[J], Amer J Ind Med, 1996, 29:227-235.

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