期刊文献+

肝细胞生长因子对主要器官/组织损伤的修复作用 被引量:11

Reparative effect of heptocyte growth factor on injured organs and tissues
在线阅读 下载PDF
导出
摘要 肝细胞生长因子(HGF)是一种多功能的生长因子,它参与多种细胞的增殖、迁移和形态发生。HGF对多种成熟的器官/组织有营养修复作用,促进肝、肾、肺等损伤器官的再生,同时也是神经系统新的营养因子之一。本文综合近年来有关文献对HGF在主要器官或组织损伤中的修复作用作一概括性介绍。 Hepatocyte growth factor(HGF),a pleiotrophic growth factor,exerts mitogenic,motogenic and morphogenic activities in various cell types.HGF is an organotrophic factor for reparative of mature organs such as liver,kidney and lung.It also belongs to the family of neurotrophic factors.Based on the relevant research articles,this review gives a summary of knowledge of reparative effect of HGF on injured organs or tissues.
出处 《生物技术通讯》 CAS 2003年第3期214-217,共4页 Letters in Biotechnology
关键词 肝细胞生长因子 器官 组织 损伤 修复作用 hepatocyte growth factor injury repair
  • 相关文献

参考文献41

  • 1林善錟.当代肾脏病学[M].上海:上海科技教育出版社,2001.165.
  • 2Nakayama N, Kashiwazaki H, Kobayashi N, et al. Differing distribution of hepatocyte growth factor-positive cells in the liver of LEC rats with acute hepatitis, chronic hepatitis and hepatoma [J]. Jpn J Cancer Res,1995,86:5.
  • 3Ishiki Y, Ohinishi H, Muto Y, et al. Direct evidence that hepatocyte growth factor is a hepatotrophic factor for liver regeneration and has a potent antihepatitis effect in vivo[J]. Hepatology, 1992,16(5):1227.
  • 4Seto S, Kaido T, Yamaoka S, et al. Hepatocyte growth factor prevents lipopolysaccharide-induced hepatic sinusoidal endothelial cell injury and intrasinusoldal fibrin deposition in rats[J]. J Surg Res, 1998,80(2):194.
  • 5Matanda Y, Matsumoto K, Yamada A, et al. Preventive and therapeutic effects in rats of hepatocyte growth factor infusion on liver fibrosis/scirrhosis[J]. Hepatology, 1997,26(1):81.
  • 6Tahara M, Matsumoto K, Nukiwa T, et al. Hepatocyte growth factor leads to recovery from alcohol-induced fatty liver in rats[J]. J Clin Invest, 1999,103(3):313.
  • 7Ohmichi H, Matsumoto K, Nakamura T. In vivo mitogenic action of lung epithelial cells: pulmonotrophic role in lung regeneration[J]. Am J Physiol, 1999,270:L1031.
  • 8Liu XL, Sato S, Dai W, et al. The protective effect of hepatocyte growth-promoting factor (pHGF) against hydrogen peroxide-induce acute lung in rats[J]. Med Electron Microsc, 2001,34(2):92.
  • 9Yamada T, Hisanaga M, Nakajima Y, et al. Enhanced expression of hepatocyte growth factor by pulmonary ischemia-reperfusion injury in the rat[J]. Am J Reapir Grit Care Med, 2000,162:707.
  • 10Sakamaki Y, et al. Hepatocyte growth factor stimulates proliferation of respiratory epithelial cells during postpnenmonectomy compensatory lung growth in mice[J]. Am J Respir Cell Mol Biol, 2002,26(5):525.

共引文献1

同被引文献81

引证文献11

二级引证文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部