摘要
目的 探讨呼吸机相关性肺炎 (VAP)的病原菌及其耐药性 ,为防治 VAP提供科学依据。方法 对 2 38例VAP患者的发病年龄、基础疾病、病原菌分布及革兰阴性杆菌耐药率进行调查分析。结果 老年 VAP患者占84 .9% ;VAP病原菌以 G- 杆菌为主 ,占菌株总数的 76 .5 % ,其中铜绿假单胞菌居首位 ;产超广谱 β-内酰胺酶细菌分离率为 35 .1% ,甲氧西林耐药金黄色葡萄球菌占金黄色葡萄球菌总数的 4 5 .8% ;G- 杆菌对常用抗菌药物已表现出较高的耐药率。结论 提倡严密动态监测 VAP病原菌 ,合理使用抗生素 ,以达到有效控制 VAP的目的。
OBJECTIVE To explore pathogens and drug resistance in ventilator associated pneumonia (VAP), and to provide the corresponding clinical prevention strategies. METHODS The ages, underlying diseases, pathogens distribution and resistance rate of Gram negative bacilli of 238 VAP cases were investigated. RESULTS From them 84.9% cases were aged patients. Among all pathogens caused VAP, Gram negative bacilli accounted for 76.5%, in which Pseudomonas aeruginosa contributed majority, and ESBLs accounted for 35.1%. MRSA contributed 45.8% in Staphylococcus aureus isolates. All these indicated that emergence of high resistance rate to common used antibiotics in Gram negative bacilli. CONCLUSIONS To effectively control VAP, extensive and dynamical monitoring of VAP pathogens and rational use of antibiotics were advocated.
出处
《中华医院感染学杂志》
CAS
CSCD
2003年第7期696-698,共3页
Chinese Journal of Nosocomiology
关键词
呼吸机相关性肺炎
病原菌
耐药性
Ventilator associated pneumonia(VAP)
Pathogen
Drug resistance
