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脂肪肝辨证分型与胰岛素抵抗的相关性研究 被引量:9

Study on Relationship between lnsulin Resistance and Syndrome Differentiation Typing in Fatty Liver
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摘要 目的 :探讨脂肪肝患者胰岛素抵抗与中医辨证分型之间的内在联系。方法 :筛选脂肪肝患者 52例及健康对照组 1 5例 ,分别测定其空腹血糖、胰岛素水平并与对照组作胰岛素敏感性比较 ,并进一步对脂肪肝患者胰岛素敏感性与中医辨证分型作多因素回归分析。结果 :(1 )脂肪肝各证型与健康对照组比较均存在明显的胰岛素抵抗 ;(2 )肝郁气滞型、痰浊内阻型、气血瘀阻型 3型之间的胰岛素敏感性比较 ,其差别无统计学意义 ,而与肝肾亏虚型比较胰岛素敏感性均显著降低 ,肝肾亏虚型与健康对照组最接近 ;(3)胰岛素敏感性与中医辨证分型密切相关。结论 Objective:To investigate the internal relationship between insulin resistance and TCM syndrome differentiation typing(SDT)in fatty liver patients Method:52 cases of fatty liver patients and 15 cases in healthy control group were selected and divided into 4 types:stagnation of liver qi,stagnation of phlegm in the interior,stagnation of qi and blood and deficiency of liver and kidney,respectively measure their fasting blood glucose and insulin level and compare with the insulin sensitivity of control group,further make regression analysis on many factors of the insulin sensitivity and TCM SDT of fatty liver patients Result:(1)Compared with healthy control group,all syndromes of fatty liver have marked insulin resistance;(2)Compared between 3 types of stagnation of liver qi,stagnation of phlegm in the interior and stagnation of qi and blood,there's no obvious difference statistically,while compared with the type of deficiency of liver and kidney,their insulin sensitivity is markedly lowered,the type of deficiency of liver and kidney is very similar to healthy control group;(3)Insulin sensitivity is closely related with TCM SDT.Conclusion:Insulin resistance is the pathological basis of TCM SDT in fatty liver
出处 《浙江中医学院学报》 2003年第4期32-34,共3页 Journal of Zhejiang College of Traditional Chinese Medicine
关键词 脂肪肝 辨证分型 胰岛素抵抗 相关性研究 空腹血糖 胰岛素 fatty liver,SDT,insulin resistance
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