摘要
目的 探讨尽早应用无创机械通气以纠正低氧血症的技术可行性并评价其治疗效果。方法 选择接受无创机械通气的低氧血症病例 16例设为治疗组 ,以经鼻面罩压力支持通气 +呼气末正压通气 (PSV+PEEP) ,待低氧血症纠正后撤机 ;选择同期住院同样病情的低氧血症病例 16例接受简易面罩设为对照组 ,两组吸入氧浓度(Fi O2 )均为 4 1% ,观察 5分钟后血氧饱和度 (Sa O2 )及 30分钟后血气。结果 治疗组与对照组治疗前各项指标相仿(P>0 .0 5 )。给予面罩 5分钟后 Sa O2 分别为 94 .7± 5 .3和 81.1± 7.2 % ,P<0 .0 1;30分钟后氧合指数 331.2± 18.3和 2 2 0 .3± 14 .5 mm Hg,P<0 .0 5 ;Pa CO2 4 5 .6± 7.1和 6 1.7± 5 .6 mm Hg,P<0 .0 5。结论 因各种病因所致的低氧血症尽早使用经鼻面罩无创机械通气可明显纠正低氧血症 。
Objective To estimate the feasibility and the efficacy of early execution noninvasive mechanical ventilation (NIMV) on those who had nonhypercapnic hypoxemia.Methods From Feb. 2001 to Nov. 2002, 32 patients who had acute respiratory failure (ARF) with hypoxemia were involved in the study. Sixteen cases by NIMV via facial mask were the study group. At the same time of hospitalization, other 16 cases with similar clinical characteristics who received simple facial mask were used as the controls. The fraction of inspired oxygen (FiO 2) of the two groups was 41%.Results For the study group and the control group, 5 minutes after using the mask, SaO 2 values were 94.7±5.3 vs 81.1±7.2% mmHg respectively for the two groups: P<0.01; 30 minutes after using the mask, PaO 2/FiO 2 values were 331.2±18.3 and 220.3±14.5 mmHg for the two groups respectively: P<0.05 and PaCO 2 45.6±7.1 vs 61.7±5.6 mmHg, P>0.05, for the two groups, respectively.Conclusion For the ARF patients with hypoxemia who had severe pulmonary infection, pancreatitis and sepsis, an early execution NIMV may significantly improve hypoxemia but may not influence the carbon dioxide.
出处
《临床肺科杂志》
2003年第5期401-402,共2页
Journal of Clinical Pulmonary Medicine
关键词
低氧血症
面罩
无创机械通气
Hypoxemia Facial mask Noninvasive mechanical ventilation
