摘要
目的 :探讨腹膜后腹腔镜肾囊肿去顶减压术对机体应激反应的影响。方法 :随机将肾囊肿 35例分成腹膜后腹腔镜组与开放手术组 ,分别于术前 2 4h和术后第 1、3天测定血白细胞总数 (WBC)、血清C 反应蛋白质 (CRP)和白细胞介素 6 (IL 6 )的浓度 ,并比较两组的平均手术时间 ,术中出血量 ,术后平均引流量 ,镇痛用药量 ,发热率 ,平均住院日和费用。结果 :开放手术组术后第 1天WBC计数比术前明显升高 (P <0 0 1) ,腹膜后腹腔镜组升高不明显 (P >0 .0 5 )。两组术后第 1、3天血清CRP和IL 6水平高于术前 (P <0 .0 5 ) ,开放手术组血清CRP和IL 6明显高于后腹腔镜组 (P <0 .0 1)。与开放手术相比 ,腹膜后腹腔镜手术具有出血少 ,引流量少 ,术后发热率低 ,用药少 ,住院日短等优点。结论 :腹膜后腹腔镜肾囊肿去顶术对机体的应激反应较开放手术低 。
Objective:To investigate Effect of laparoscopic resection of renal cyst via retroperitoneam on systemic emergency reaction.Methods:35 patients with renal cyst were randomly divided into two groups: retroperitoneal laparoscopy group and laparotomy group. WBC counts, serum C reactive protein(CRP) and interleukin 6 were measured on the preoperative day before operation and on the 1?3 day after operation. The mean operative time, blood loss,drainage after operation, the dose of analgesia drug, fever mobidity, postoperative hospitalization and cost were analyzed.Results:The WBC counts of the first day after operation were significantly higher than those of preoperation in the laparotomy group (P<0.05), while no significant increase in the retroperitoneal laparoscopic group (P>0.05). But the serum CRP and IL 6 levels of laparotomy group showed more significant difference than those of retroperitoneal laparoscopic group (P<0.01). Compared with laparotomy, retroperitoneal laparoscopic operation had many advantages such as less bleeding and drainage, lower fever mobidity, analgesia drug using and shorter hospital stay.Conclusions:Laparoscopic resection of renal cyst via retroperitoneal laparoscopy induce more faintish response of body than laparotomy. It is expected to replace the traditional operation.
出处
《腹腔镜外科杂志》
2003年第3期171-173,共3页
Journal of Laparoscopic Surgery
基金
石河子市科研基金资助项目
