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宣降肺气方治疗慢性肺源性心脏病急性发作期临床研究 被引量:3

Clinical study on treatment with Xuanjiang Feiqimixture(宣降肺气方) for acute seizure phase of chronic cor pulmonale
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摘要 目的 :探讨宣降肺气方结合西药对慢性肺源性心脏病 (肺心病 )急性发作期的疗效。方法 :6 2例肺心病急性发作期患者随机分为两组 ,各 31例 ,治疗组在常规西药治疗基础上加服宣降肺气方 ,对照组单用常规西药治疗。治疗后 10 d测定两组患者血浆内皮素 1(ET 1)水平及血气分析等指标 ,并进行临床疗效分析。结果 :治疗组显效率为 6 7.74 % ,明显高于对照组的 4 1.94 % (P<0 .0 5 ) ;两组治疗后的 ET 1水平、氧分压、二氧化碳分压均较治疗前明显改善 (P<0 .0 5或 P<0 .0 1) ,但治疗组更优于对照组 (P均 <0 .0 5 )。结论 :在常规治疗基础上加用宣降肺气方治疗肺心病急性发作期 ,可明显提高疗效。 Objective: To observe the curative efficacy of Xuanjiang Feiqi mixture(XJFQM,宣降肺气方) combined with western medicine(WM) for acute seizure phase of chronic cor pulmonale. Methods: Sixtytwo cases with acute seizure phase of cor pulmonale were randomly divided into two groups. The treatment group( n=31 ) was treated with both conventional therapy of WM and XJFQM, and the control group( n=31 ) was treated with conventional WM therapy described above only. Ten days after the treatment, the level of plasma endothelin1(ET1) and blood gas indices were detected in both groups, and the therapeutic effects were observed . Results: The markedly effective rate of the treatment group(67.74%) was higher than that of the control group(41.94%, P <0.05). Meanwhile the improvements of plasma ET1,partial pressure of oxygen in artery(PaO 2), partial pressure of carbondioxide in artery (PaCO 2) in each group after the treatment were more obvious than that before the treatment( P <0.05 or P <0.01), and the changing extend were more obviously in treatment group than that in control group (all P <0.05). Conclusion: The treatment of XJFQM combined WM for acute seizure phase of chronic cor pulmonale is able to heighten the curative efficacy significantly .
出处 《中国中西医结合急救杂志》 CAS 2003年第5期285-286,共2页 Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
基金 四川省中医管理局科研基金资助项目 (960 3 1)
关键词 宣降肺气方 中医药治疗 慢性肺源性心脏病 急性发作期 临床研究 内皮素-1 acute seizure phase of cor pulmonale endothelin1 Xuanjiang Feiqi mixture
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