摘要
本文报道用电镜观察 Wistar 大鼠的肝、脾、肺和小肠等组织,表明其内存在少量的隐窝细胞。这种细胞具有以下形态特征:1.胞质内有界膜包绕的电子致密颗粒;2.胞质内有含杆状核心的小泡;3.胞核多偏于一侧,异染色质集聚于核周边;4.有发育良好的伪足突起。另外,在3例人乳腺癌组织中也见到有此形态特征的隐窝细胞。根据其分布与形态特点,初步推测它们属于自然杀伤细胞,在肿瘤中可能发挥细胞毒或免疫防御作用。
By electron microscopic observation,we found few pit cells in liver,spleen.
lungs,and small intestine in Wistar rat.The pit cells show several morphological
characteristics as follows:1.electron dense granules in cytoplasm,which are
surrounded by a limiting membrane;2.vesicles with rod shaped bodies in
cytoplasm;3.eccentric nucleus with marginal heterochromatin;4.well developed
pseudopodia.In addition,the pit cells have also been found in breast carcinoma in
3 patients.According to their distribution and morphology,we preliminarily
deduced they probably belong to natural killer cells and may act as a cytotoxic
agent and an immunological defender against carcinoma.
出处
《解剖学报》
CAS
CSCD
北大核心
1989年第2期202-204,共3页
Acta Anatomica Sinica
关键词
隐窝细胞
大鼠
人
乳腺癌
Pit cells
Rat
Human breast carcinoma
Electron microscopy
