摘要
目的 :探讨苯作业工人血清中细胞因子白细胞介素 -6(IL-6)、肿瘤坏死因子 (TNF)的变化及其意义。方法 :用放射免疫法 ,对不同工龄的苯作业工人血清中IL-6,TNF浓度进行检测 ,并同白细胞变化进行对照比较。结果 :接苯作业工人血清中IL-6 ,TNF较对照组有明显升高 (P<0.05,P<0.01) ,且这些变化在白细胞明显降低前即已发生。结论 :苯作业可致工人血清TNF,IL-6水平的增高 ,这对苯中毒的早期诊断有一定意义。
Objective:To approach the changes on IL-6and TNF in workers exposed to benzene and their meanˉings.Methods:The serumconcentration of IL-6and TNF were measured in workers with different benzene exposure period,and were compared with white blood cell count.Results:IL-6and TNF were higher in workers exposed to benzene than those in control group(P<0.05),and those changes happened earlier than the decrease of white blood cell count.Conclusion:Monitoring IL-6and TNF in the serum may be a valuable index in diagnosing benzene poiˉsoning in early period.
出处
《安全、健康和环境》
2004年第1期16-17,共2页
Safety Health & Environment
