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妊娠期肝内胆汁淤积症的研究进展 被引量：7

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摘要 妊娠期肝内胆汁淤积症(ICP)是性激素、家族遗传、免疫、环境等多因素相互作用的结果;高浓度胆汁酸引起胎盘、脐血管异常收缩进而使胎儿宫内急性缺氧。及早发现病情并了解严重程度,辅以综合的药物治疗,加强母儿监测,适时结束妊娠可改善母儿不良处境。
作者 韩平 邹丽
机构地区 华中科技大学附属协和医院妇产科
出处 《国外医学（妇产科学分册）》 2003年第6期343-346,共4页 Foreign Medical Sciences(Obstet Gynecol Fascicle)
关键词 妊娠期 肝内胆汁淤积症 研究进展 病因 监测 治疗
分类号 R714.25 [医药卫生—妇产科学]
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参考文献20

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  • 3Oude Elferink RP, van Berge Henegeuwen GP. Cracking the genetic code for benign recto'rent and progressive familial intrahepatic cholestasis. J Hepato1,1998, 29(2): 317-320.
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同被引文献37

  • 1杨慧霞,周世梅.妊娠期糖尿病胎盘病理分析[J].中华妇产科杂志,1993,28(12):714-716. 被引量：16
  • 2丁依玲,付霞霏.妊娠肝内胆汁淤积症胎儿总胆汁酸浓度与肾上腺皮质功能变化的关系[J].中华围产医学杂志,2005,8(3):168-170. 被引量：9
  • 3王金娥.妊娠期内胆汁淤积症30例分析[J].实用医技杂志,2006,13(21):3906-3907. 被引量：2
  • 4曹泽毅.中华妇产科学（第1版）[M].北京:人民卫生出版社,1999.35-37.
  • 5Athanassisades A,Hamilton GS,Lala PK.Vascular endothelial growth factors stimulates proliferation but not migration or invasiveness in human extravillous trophoblast [J ].Biol Reprod,1998,59 (3):643-654.
  • 6Sepulveda WH,Gonzalez C,Cruz MA,et al.Vasoconstrictive,effect of bile acids on isolated human placental chorionic veins [J ].Eur J Obster Grynecol Reprod Biol,1991,42 (3):211-215.
  • 7Harkness UF,Mari G.Diagnosis and management of intrauterine growth restriction[J].Clin perinatol,2004,31:743 ～ 746
  • 8Brites D, Rodrigues CM, van-ZelleRH, et al. Relevance of serum bile acid profile in the diagnosis of intrahepatic cholestasis of pregnancy in an high incidence area: Portugal [J]. EuRJ Obstet Gynecol Reprod Biol, 1998,80 : 31-38.
  • 9刘伯宁 沈宁 等.妊娠期肝内胆汁淤积及胎盘的组织计量测定[J].中华妇产科杂志,1988,23:9-12.
  • 10Kramer MS, Usher RH, Pollack R, et al. Etiologic determinants of abruptio placentae [J]. Obstet Gynecol,1997,89(2) :221

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国外医学（妇产科学分册）
2003年 第6期

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