摘要
本研究表明体外激活扩增的CD_3AK细胞可以MHC非限制性方式杀伤MHC I类抗原阴性NK敏感的K562细胞和MHC I类抗原阴性NK不敏感的Daudi细胞,杀瘤机制与诱导靶细胞坏死和/或凋亡有关。
The result showed that CD3AK induced and expanded in vitro could kill MHC I class - negative K562 (NK - sensitive) and Daudi (NK - resistant) tumor cells in a MHC - nonrestricted manner. Induction of necrosis and / or apoptosis of target cells were responsible for the tumorlytic effect mediated by CD3AK.
出处
《中国肿瘤生物治疗杂志》
CAS
CSCD
1996年第3期211-213,共3页
Chinese Journal of Cancer Biotherapy
基金
国家八五攻关专题(85-914-02-08)
国家自然科学基金项目(39270754)
